Total synthesis of (+)-preussin: Control of the stereogenic centers by enantioselective allyltitanations
Total synthesis of (+)-preussin: Control of the stereogenic centers by enantioselective allyltitanations
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DOI：
10.1055/s-2004-829564
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发表时间：
2004-08-09
期刊：
影响因子：
2
通讯作者：
Cossy, J
中科院分区：
文献类型：
--
作者：
Canova, S;Bellosta, V;Cossy, J
以苯乙醛为原料，经10步反应合成了（+）-普鲁辛，总收率6.4%。这三个立体异构中心是由醛的不对称烯丙基钛化反应控制的。
(+)-Preussin was synthesized in ten steps with an overall yield of 6.4% from phenylacetaldehyde. The three stereogenic centers were controlled by enantioselective allyltitanations of aldehydes.