POST-HEPARIN LIPASES, LIPIDS AND RELATED HORMONES IN MEN UNDERGOING CORONARY ARTERIOGRAPHY TO ASSESS ATHEROSCLEROSIS
POST-HEPARIN LIPASES, LIPIDS AND RELATED HORMONES IN MEN UNDERGOING CORONARY ARTERIOGRAPHY TO ASSESS ATHEROSCLEROSIS
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DOI：
10.1016/0021-9150(83)90041-2
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发表时间：
1983-01-01
期刊：
影响因子：
5.3
通讯作者：
BIRKENHAGER, JC
中科院分区：
文献类型：
--
作者：
BARTH, JD;JANSEN, H;BIRKENHAGER, JC
肝素后脂肪酶活性测定在正常血脂男性投诉提示症状性冠状动脉疾病。一个研究组，谁表现出弥漫性动脉粥样硬化狭窄的冠状动脉血管，通过定量计算机辅助分析方法进行评估，有一个降低的肝脂肪酶与正常的血管造影组相比。研究组的脂蛋白脂肪酶较低，但在正常范围内，无统计学差异。一些相关激素（皮质醇、雌二醇、睾酮和胰高血糖素）在两组中存在差异，而其他激素（胰岛素、人生长激素、催乳素、甲状腺激素）则无差异。结果进行了讨论，鉴于拟议的作用，肝脂肪酶在摄取HDL [高密度脂蛋白胆固醇]的肝脏。
Post-heparin lipase activities were measured in normolipemic men with complaints suggestive of symptomatic coronary artery disease. A study group, who showed diffuse atherosclerotic narrowing of the coronary vessels, as assessed by a quantitative computer-assisted analysis method, had a lowered hepatic lipase in comparison with a group with normal angiograms. Lipoprotein lipase was lower in the study group but well within the normal range and not statistically different. Some related hormones (cortisol, estradiol, testosterone and glucagon) were different in the 2 groups while others (insulin, human growth hormone, prolactin, thyroid hormones) were not. The results are discussed in view of the proposed role of hepatic lipase in the uptake of HDL [high density lipoprotein-cholesterol] by the liver.