Labeling of mesenchymal stem cells by bioconjugated quantum dots
Labeling of mesenchymal stem cells by bioconjugated quantum dots
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DOI:
10.1021/nl071547f
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发表时间:
2007-10-01
期刊:
影响因子:
10.8
通讯作者:
Mao, Jeremy J.
中科院分区:
文献类型:
--
作者:
Shah, Lhranti S.;Clark, Paul A.;Mao, Jeremy J.
Long-term labeling of stem cells during self-replication and differentiation benefits investigations of development and tissue regeneration. We report the labeling of human mesenchymal stem cells (hMSCs) with RGD-conjugated quantum dots (QDs) during self-replication, and multilineage differentiations into osteogenic, chondrogenic, and adipogenic cells. QD-labeled hMSCs remained viable as unlabeled hMSCs from the same subpopulation. These findings suggest the use of bioconjugated QDs as an effective probe for long-term labeling of stem cells.