POLYALKYLATED CYCLOPENTINDOLES - CYTOTOXIC FISH ANTIFEEDANTS FROM A SPONGE, AXINELLA SP

POLYALKYLATED CYCLOPENTINDOLES - CYTOTOXIC FISH ANTIFEEDANTS FROM A SPONGE, AXINELLA SP
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DOI:
10.1016/s0040-4020(01)88399-x
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发表时间:
1990-01-01
期刊:
影响因子:
2.1
通讯作者:
PAUL, VJ
PAUL, VJ
中科院分区:
化学3区
文献类型:
--
作者:
HERB, R;CARROLL, AR;PAUL, VJ

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西澳大利亚海绵Axinella sp.产生了三个C3上未被取代的多烷基吲哚,因此显然不是来自色氨酸。这三种化合物是除草剂A、B和C,对KB细胞具有细胞毒性,是鱼类拒食剂。
A Western Australian sponge, Axinella sp., yielded three polyalkylated indoles unsubstituted at C3, thus apparently not derived from tryptophan. The three compounds, herbindoles A, B, and C, are cytotoxic against KB cells and are fish antifeedants.