NUCLEOSOME CORES HAVE 2 SPECIFIC BINDING-SITES FOR NON-HISTONE CHROMOSOMAL-PROTEINS HMG-14 AND HMG-17
NUCLEOSOME CORES HAVE 2 SPECIFIC BINDING-SITES FOR NON-HISTONE CHROMOSOMAL-PROTEINS HMG-14 AND HMG-17
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DOI：
10.1126/science.7433974
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发表时间：
1980-01-01
期刊：
影响因子：
56.9
通讯作者：
OLINS, DE
中科院分区：
文献类型：
--
作者：
MARDIAN, JKW;PATON, AE;OLINS, DE
HMG 14（或 17）与核小体核心的结合在非变性聚丙烯酰胺凝胶上产生 2 个主要的附加条带。结合的 HMG 14 改变了由 DNase I 消化重建的聚（脱氧腺苷酸-脱氧胸苷酸）核小体核心产生的末端标记 DNA 片段分布的相对密度。核小体核心可能有 2 个 HMG 14（或 17）的特异性结合位点。
The binding of HMG 14 (or 17) to nucleosome cores produces 2 major additional bands on nondenaturing polyacrylamide gels. Bound HMG 14 alters the relative densities of the end-labeled DNA fragment distribution produced by DNase I digestion of reconstructed poly(deoxyadenylate-deoxythymidylate) nucleosome cores. Nucleosome cores may have 2 specific binding sites for HMG 14 (or 17).