Similar activation patterns in the prefrontal cortex for Chinese and Japanese verbal fluency tests with syllable cues as revealed by near-infrared spectroscopy
Similar activation patterns in the prefrontal cortex for Chinese and Japanese verbal fluency tests with syllable cues as revealed by near-infrared spectroscopy
复制标题
DOI：
10.1080/13803395.2020.1825637
复制
发表时间：
2020-09
影响因子：
2.2
通讯作者：
Mingqiao Song;M. Suda;Y. Aoyama;Y. Takei;Toshimasa Sato;M. Fukuda;M. Mikuni
中科院分区：
文献类型：
--
作者：
Mingqiao Song;M. Suda;Y. Aoyama;Y. Takei;Toshimasa Sato;M. Fukuda;M. Mikuni
语言流畅性测验（VFT）是神经心理学中用来评价人脑前额叶皮层（PFC）认知功能的一种测验。我们提出了一个新的中国VFT类似于建立日本VFT，这两个测试提示一个音节的主题。然而，目前尚不清楚中国VFT是否可以激活PFC，以及PFC激活模式是否在两个测试之间相似。在这里，我们对30名母语为汉语的人和30名母语为日语的人进行了汉语VFT和日语VFT。我们使用近红外光谱（NIRS）观察PFC激活。然后，我们比较了中日VFT的相似性。受试者在汉语VFT中平均产生12.8 ± 4.7个词。近红外光谱显示，试验期间氧合血红蛋白浓度显著高于试验前和试验后。它表现出类似的PFC激活模式与日本VFT。新的汉语VFT能有效地激活汉语使用者的前额叶皮层。因此，我们的工作提供了第一个有效的语音提示的中文VFT，从其他非严格的音素中文VFT独特的，并有利于各种PFC相关的认知障碍的诊断。
ABSTRACT The verbal fluency test (VFT) is utilized in neuropsychology to evaluate the cognitive function of the prefrontal cortex (PFC) in the human brain. We present a novel Chinese VFT similar to the established Japanese VFT; both tests prompt a syllable to the subject. However, it was uncertain whether the Chinese VFT can activate the PFC and whether PFC activation patterns are similar between the two tests. Here we administered the Chinese VFT to 30 native Chinese speakers and the Japanese VFT to 30 native Japanese speakers. We used near-infrared spectroscopy (NIRS) to observe PFC activation. Then we compared the similarities between the Chinese VFT and the Japanese VFT. The subjects generated an average of 12.8 ± 4.7 words during the Chinese VFT. NIRS indicates that the concentration of oxygenated hemoglobin during the test was significantly higher than those before and after the test. It exhibited similar PFC activation patterns with the Japanese VFT. The novel Chinese VFT can activate the PFC in the human brain effectively in Chinese speakers. Our work thus provides the first validated phonetically cued Chinese VFT, unique from other not strictly phonemic Chinese VFTs, and facilitates the diagnosis of various PFC-related cognitive impairments.