Leptin concentrations in response to acute stress predict subsequent intake of comfort foods.
Leptin concentrations in response to acute stress predict subsequent intake of comfort foods.
复制标题
响应急性压力的瘦素浓度可预测随后摄入的舒适食物。
DOI：
10.1016/j.physbeh.2012.04.021
复制
发表时间：
2012
影响因子：
2.9
通讯作者：
Epel,ElissaS
中科院分区：
文献类型：
--
作者：
Tomiyama,AJanet;Schamarek,Imke;Lustig,RobertH;Kirschbaum,Clemens;Puterman,Eli;Havel,PeterJ;Epel,ElissaS
动物和人类都表现出在急性压力后吃更多“安慰食物”（高脂肪，甜的食物）的倾向。这种应激性进食可能是导致肥胖流行的原因之一，了解其潜在的心理生物学机制是很重要的。先前的研究已经研究了是什么让人在压力后吃得更多;这项研究调查了是什么可能让人吃得更少。瘦素已经被证明在实验室压力源后增加，并且已知调节饱腹感。这项研究探讨了瘦素反应性是否解释了应激性进食的个体差异。为了验证这一点，我们将40名妇女暴露于标准化的急性心理实验室压力（特里尔社会压力测试），同时重复采血测量血浆瘦素。然后我们测量了压力源后的食物摄入量。在应激过程中增加瘦素预测安慰性食物的摄入量较低。这些初步研究结果表明，瘦素的急剧变化可能是调节压力后安慰食品消费的因素之一。
Both animals and humans show a tendency toward eating more “comfort food” (high fat, sweet food) after acute stress. Such stress eating may be contributing to the obesity epidemic, and it is important to understand the underlying psychobiological mechanisms. Prior investigations have studied what makes individuals eat more after stress; this study investigates what might make individuals eat less. Leptin has been shown to increase following a laboratory stressor, and is known to regulate satiety. This study examined whether leptin reactivity accounts for individual differences in stress eating. To test this, we exposed forty women to standardized acute psychological laboratory stress (Trier Social Stress Test) while blood was sampled repeatedly for measurements of plasma leptin. We then measured food intake after the stressor. Increasing leptin during the stressor predicted lower intake of comfort food. These initial findings suggest that acute changes in leptin may be one of the factors modulating down the consumption of comfort food following stress.