A 12-year follow-up of a treated cocaine-dependent sample

A 12-year follow-up of a treated cocaine-dependent sample
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DOI:
10.1016/j.jsat.2005.12.007
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发表时间:
2006-04-01
影响因子:
3.9
通讯作者:
Rawson, R
Rawson, R
中科院分区:
医学2区
文献类型:
--
作者:
Hser, YI;Stark, ME;Rawson, R

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这项研究检查了可卡因依赖样本中的长期结果(死亡率、药物使用、精神健康、就业、犯罪参与)。这项为期12年的跟踪研究于2002-2003年进行,更新了1990-1991年和1991-1992年对321名在1988-1989年接受戒毒治疗的男性可卡因依赖退伍军人进行的两次面谈中获得的最新信息。在2002-2003年的后续行动中,28人死亡,266人接受采访。检验纵向关系的混合模型表明,在进入指数治疗后的12年内,治疗与较低水平的可卡因使用和更稳定的恢复(即至少5年内持续戒除可卡因)有关。在吸食时,几乎没有什么指标预测到后续的稳定恢复:只是白人(与非裔美国人相比),并且对在高风险情况下避免使用可卡因的能力有更大的信心。在访谈前的一年中,获得稳定康复的个人报告较少的精神症状、参与犯罪和失业。对于大量长期使用可卡因的可卡因依赖者来说,不良后果是显而易见的。(C)2006 Elsevier Inc.保留所有权利。
The study examined long-term outcomes (mortality, substance use, mental health, employment, criminal involvement) among a cocaine-dependent sample. This 12-year follow-up study, conducted in 2002-2003, updates information obtained at intake and two face-to-face interviews conducted in 1990-1991 and 1991-1992 among 321 male cocaine-dependent veterans admitted to drug treatment in 1988-1989. At the 2002-2003 follow-up, 28 had died and 266 were interviewed. A mixed model examining the longitudinal relationships demonstrated that treatment was associated with lower levels of cocaine use over the 12-year follow-tip period after entry into the index treatment and more stable recovery (i.e., continuously abstinent from cocaine for at least 5 years). Few measures at intake predicted stable recovery at follow-up: only being White (vs. being African American) and having greater confidence in ability to avoid cocaine use in high-risk situations. Individuals achieving stable recovery reported less psychiatric symptoms, criminal involvement, and unemployment during the year prior to the interview. Adverse outcomes were apparent for a significant number of cocaine-dependent users who continued to use cocaine for a long period. (c) 2006 Elsevier Inc. All rights reserved.