Change in hospital antibiotic use and acquisition of multidrug-resistant gram-negative organisms after the onset of coronavirus disease 2019.

Change in hospital antibiotic use and acquisition of multidrug-resistant gram-negative organisms after the onset of coronavirus disease 2019.
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DOI:
10.1017/ice.2020.1360
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发表时间:
2021-09
影响因子:
4.5
通讯作者:
Heil EL
Heil EL
中科院分区:
医学4区
文献类型:
--
作者:
Bork JT;Leekha S;Claeys K;Seung H;Tripoli M;Amoroso A;Heil EL

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进行了中断时间序列分段回归,以确定一家学术医院中抗生素使用和多重耐药革兰氏阴性菌(MDRGN)获得相对于COVID-19的趋势。与二零一九年的类似日历期间相比,新型冠状病毒爆发后的期间抗生素使用总量及与肺炎相关的抗生素使用量较高。此外,每周COVID-19阳性检测每增加一次,MDRGN的收购就增加3%。
Interrupted time series segmented regression was conducted to trend antibiotic use and multidrug-resistant gram-negative (MDRGN) acquisition relative to COVID-19 in an academic hospital. Total antibiotic use and antibiotic use related to pneumonia was higher in the period after the onset of COVID-19 compared to the similar calendar period in 2019. Furthermore, MDRGN acquisition increased 3% for every increase in positive COVID-19 tests per week.
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