Relationship of evaporative rates to serum [Na+], [K+], and osmolarity in acute heat stress.
Relationship of evaporative rates to serum [Na+], [K+], and osmolarity in acute heat stress.
复制标题
急性热应激时蒸发率与血清 [Na ]、[K ] 和渗透压的关系。
DOI：
10.1152/jappl.1968.25.2.149
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发表时间：
1968
影响因子：
3.3
通讯作者：
L. C. Senay
中科院分区：
文献类型：
--
作者：
L. C. Senay
方法五名男性医学生作为十月和十一月期间进行的实验对象。没有受试者有热适应所需的事件史(1)。他们在接触热源之前至少 6 小时禁食，但不禁水。大约上午 5:30 到实验室报到后，受试者穿着全套衣服，在室温（25-27°C）下躺了 30 分钟。获得静脉血样本后，受试者脱掉衣服，进入加热室（43.3 C DB，29 C WB），称重，并立即开始运动。锻炼包括在每半小时热暴露的前 10 分钟以足以产生 400-450 kg-m/min 的工作负荷的速度上下 0.3 m 高的凳子。在工作时间之间，受试者在帆布床上休息。所有实验均在上午 5:30 至 10:30 之间进行。由于血液样本是从最初的暴露前休息时间开始计时的，因此一天中从一个受试者到另一个受试者采集样本的时间之间存在最大 30 分钟的差异，尽管每个单独实验中的样本间隔是相同的。每个受试者都经历了两次热暴露，两次暴露之间的时间间隔至少为 1 周。实验变化为： 补液——称重前 30 分钟摄入 300 g 温热的 0.1% 盐水 (27)，并在受试者称重后立即摄入额外称量的盐水（每小时一次）以维持体重；每次饮水前采集血样（间隔 30 分钟）。实验期间省略了脱水液体的摄入。
METHODSFive male medical students were subjects for experi-ments conducted during October and November. None of the subjects had a history of events necessary for heat acclimatization(1). They refrained from food, but not water, for at least 6 hr preceding heat exposure. On reporting to the laboratory at approximately 5: 30 AM, fully clothed subjects reclined for 30 min at room temperature (25-27 C). After a venous blood sample was obtained, subjects disrobed, entered the heat chamber (43.3 C DB, 29 C WB), were weighed, and immediately began to exercise. Exercise consisted of stepping on and off a stool 0.3 m high at a rate sufficient to create a work load of 400-450 kg-m/min for the first 10 min of every half-hour of heat exposure. Between work periods subjects rested on a canvas cot. All experiments were run between 5: 30 AM and 10: 30 AM. Since blood samples were timed from initial pre-exposure rest period, there was a maximum difference of 30 min between times of day that samples were taken from one subject to another, though spacing of samples within each individual experiment was identical. Each subject underwent two heat exposures with a minimum of 1 week between exposures. Experimental variations were: Rehydration-ingestion of 300 g warm 0.1% saline (27) 30 min before weighing with additional weighed amounts of saline ingested immediately after subject weighing (once per hour) was used to maintain body weight; blood samples were taken prior to each water ingestion (30-min intervals). Dehydration-fluid ingestion was omitted during the experiments.