New insights into insulin resistance pathophysiology: How it affects glucose and lipid metabolism
New insights into insulin resistance pathophysiology: How it affects glucose and lipid metabolism
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DOI：
10.1179/acb.2001.025
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发表时间：
2001-05-01
影响因子：
1.6
通讯作者：
Col, V
中科院分区：
文献类型：
--
作者：
Col, V
胰岛素抵抗是在许多生理和病理生理条件下遇到的代谢状态。它对葡萄糖和脂质代谢的关键作用越来越被认识到。在过去的几年中，许多分子/细胞内途径受这种情况下已经阐明。作者回顾了一些最近的研究结果，几个主要的代谢异常。还提供了当前和未来治疗的概述。
Insulin resistance is a metabolic state encountered in many physiological and physiopathological conditions. Its pivotal effect on glucose and lipid metabolism is increasingly recognised. Over the last few years, numerous molecular/intracellular pathways affected by this condition have been elucidated. The author reviews some recent findings underlying several major metabolic abnormalities. An overview of current and future therapeutics is also provided.