Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation, synchronisation, and continuation phases of paced finger tapping
Brain activity correlates differentially with increasing temporal complexity of rhythms during initialisation, synchronisation, and continuation phases of paced finger tapping
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DOI：
10.1016/j.neuropsychologia.2004.03.001
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发表时间：
2004-01-01
期刊：
影响因子：
2.6
通讯作者：
Miall, RC
中科院分区：
文献类型：
--
作者：
Lewis, PA;Wing, AM;Miall, RC
人类运动系统部分的活动已被证明与所执行的运动序列的复杂性相关，包括肢体移动的数量、运动的数量和轨迹的数量。在这里，我们使用过度学习的敲击任务，根据序列中产生的不同间隔的数量来搜索与时间复杂性相关的活动。我们的任务分为三个阶段：运动选择和启动（启动），同步的手指敲击与外部听觉线索（同步），并在没有听觉起搏器的情况下继续敲击（继续）。同步和持续之间的比较显示了一种模式，与以前的神经影像学研究的节奏手指轻敲。因此，双侧SMA和基底神经节的激活在连续敲击中比在同步敲击中更大。参数分析显示，在启动期间，双侧补充和前补充运动皮层（SMA和preSMA），喙背运动前皮层（PMC），基底神经节，背外侧前额叶皮层（DLPFC），以及其他领域的活动与时间复杂性相关。在同步化过程中，在双侧SMA，更多的尾侧背侧和腹侧PMC，右侧DLPFC和右侧初级运动皮层观察到相关活动。在P < 0.01（校正后，群集水平），持续期间未观察到相关活动，尽管左侧角回在P < 0.05时活跃。我们认为，在启动过程中，前SMA和嘴背PMC活动可能与时间参数的选择有关，而中央前额叶皮层在启动和同步过程中的激活可能与时间错误监测或纠正有关。在连续过程中，活动的缺乏与时间复杂性显著相关，这表明，一旦过度学习的定时运动序列被选择并启动，在没有外部线索的情况下，与其继续生产相关的定时控制过程就没有进一步的调整。(C)2004爱思唯尔有限公司保留所有权利。
Activity in parts of the human motor system has been shown to correlate with the complexity of performed motor sequences in terms of the number of limbs moved, number of movements, and number of trajectories. Here, we searched for activity correlating with temporal complexity, in terms of the number of different intervals produced in the sequence, using an overlearned tapping task. Our task was divided into three phases: movement selection and initiation (initiate), synchronisation of finger tapping with an external auditory cue (synchronise), and continued tapping in absence of the auditory pacer (continue). Comparisons between synchronisation and continuation showed a pattern in keeping with prior neuroimaging studies of paced finger tapping. Thus, activation of bilateral SMA and basal ganglia was greater in continuation tapping than in synchronisation tapping. Parametric analysis revealed activity correlating with temporal complexity during initiate in bilateral supplementary and pre-supplementary motor cortex (SMA and preSMA), rostral dorsal premotor cortex (PMC), basal ganglia, and dorsolateral prefrontal cortex (DLPFC), among other areas. During synchronise, correlated activity was observed in bilateral SMA, more caudal dorsal and ventral PMC, right DLPFC and right primary motor cortex. No correlated activity was observed during continue at P < 0.01 (corrected, cluster level), though left angular gyrus was active at P < 0.05. We suggest that the preSMA and rostral dorsal PMC activities during initiate may be associated with selection of timing parameters, while activation in centromedial prefrontal cortex during both initiate and synchronise may be associated with temporal error monitoring or correction. The absence of activity significantly correlated with temporal complexity during continue suggests that, once an overlearned timed movement sequence has been selected and initiated, there is no further adjustment of the timing control processes related to its continued production in absence of external cues. (C) 2004 Elsevier Ltd. All rights reserved.