Experimental measurement and quantification of frictional contact between biological surfaces experiencing large deformation and slip
Experimental measurement and quantification of frictional contact between biological surfaces experiencing large deformation and slip
复制标题
DOI：
10.1016/j.jbiomech.2008.01.006
复制
发表时间：
2008-01-01
影响因子：
2.4
通讯作者：
Sah, Robert L.
中科院分区：
文献类型：
--
作者：
Gratz, Kenneth R.;Sah, Robert L.
接触生物表面之间的相互作用可能在生理和病理过程中发挥重要作用。理论模型使用一个或多个简化假设描述了一些特殊的接触情况。接触的实验量化有助于验证理论分析。本研究的目的是开发一种描述接触体之间变形和相对表面运动的动力学的通用数学方法，并实现该方法来描述两个实验跟踪的组织表面之间的接触。描述了使用离散组织标记物的运动的接触的理论公式(2-D和3-D)。该方法使用理论生成的三维数据集进行了验证，对于大范围的参数，误差为1%。将该方法应用于对向关节软骨组织的接触加载，光学跟踪细胞核的位移，并用于量化表面的运动和变形。与材料特性匹配的组织相比，材料特性不匹配的组织在接触表面之间的横向扩展和相对运动(滑动)方面表现出更大的差异。(C)2008爱思唯尔有限公司。保留所有权利。
Interactions between contacting biological surfaces may play significant roles in physiological and pathological processes. Theoretical models have described some special cases of contact, using one or more simplifying assumptions. Experimental quantification of contact could help to validate theoretical analyses. The objective of this study was to develop a general mathematical approach describing the dynamics of deformation and relative surface motion between contacting bodies and to implement this approach to describe the contact between two experimentally tracked tissue surfaces. A theoretical formulation (in 2-D and 3-D) of contact using the movement of discrete tissue markers is described. The method was validated using theoretically generated 3-D datasets, with < 1% error for a wide range of parameters. The method was applied to the contact loading of opposing articular cartilage tissues, where displacements of cell nuclei were tracked optically and used to quantify the movements and deformations of the surfaces. Compared to tissues with matched material properties, tissues with mismatched material properties exhibited increased disparities in lateral expansion and relative motion (sliding) between the contacting surfaces. (c) 2008 Elsevier Ltd. All rights reserved.