The effects of prenatal stress on temperament and problem behavior of 27-month-old toddlers
The effects of prenatal stress on temperament and problem behavior of 27-month-old toddlers
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DOI：
10.1007/s00787-005-0435-1
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发表时间：
2005-02-01
影响因子：
6.4
通讯作者：
Buitelaar, JK
中科院分区：
文献类型：
--
作者：
Gutteling, BM;de Weerth, C;Buitelaar, JK
目的通过前瞻性研究探讨产前应激对婴儿气质和问题行为的影响。方法收集妊娠期未生育妇女的压力、焦虑和唾液皮质醇水平的自我报告资料。在27个月时，通过父母对婴儿特征问卷的报告来测量孩子的气质。在使用Bayley发展量表2 - 30期间，通过直接观察评估儿童的行为，并通过儿童行为检查表2 - 3上的父母报告评估儿童的行为。结果获得103名健康幼儿的完整数据。进行逻辑回归分析，并对可能的产前、围产期和产后混杂因素进行调整。怀孕期间的压力是一个预测较低水平的不安/破坏性气质（OR = 0.77），更多的总的行为问题（OR = 1.17），和更多的外化行为问题（OR = 1.12）在2岁的孩子。害怕生育残疾儿童是幼儿不安/破坏性气质水平较高（OR = 1.39）和注意力调节问题较多（OR = 1.46）的预测因子。结论母亲产前压力水平的增加似乎与幼儿的气质和行为问题有关。
Aim To examine, in a prospective study, the influence of prenatal stress on infant temperament and problem behavior. Method Self-report data on stress and anxiety, and levels of cortisol in saliva were collected from nulliparous women during pregnancy. Temperament of the child was measured at 27 months by parent report on the Infant Characteristics Questionnaire. Behavior of the child was assessed by direct observation during the administration of the Bayley Scales of Development 2 - 30, and by parent report on the Child Behavior Checklist 2 - 3. Results Complete data were available for 103 healthy toddlers. Logistic regression analyses were performed and results were adjusted for possible prenatal, perinatal and postnatal confounders. Perceived stress during pregnancy was a predictor of lower levels of restless/ disruptive temperament (OR = 0.77), more total behavioral problems (OR = 1.17), and more externalizing behavioral problems (OR = 1.12) in 2-year-olds. Fear of bearing a handicapped child was a predictor of higher levels of restless/ disruptive temperament (OR = 1.39) and more attention regulation problems in toddlers (OR = 1.46). Conclusions Increased levels of maternal prenatal stress appear to be associated with temperamental and behavioral problems in toddlers.