Moderate Accumulation of Calcium and Phosphorus in the Splenic Artery with Aging and Low Accumulation of Those in the Pulmonary Artery with Aging
Moderate Accumulation of Calcium and Phosphorus in the Splenic Artery with Aging and Low Accumulation of Those in the Pulmonary Artery with Aging
复制标题
DOI：
10.1007/s12011-007-0052-6
复制
发表时间：
2007-05
影响因子：
3.9
通讯作者：
Iria Maria Prieto Payo;Nutcharin Ongkana;S. Tohno;C. Azuma;T. Minami;Y. Moriwake;Y. Tohno
中科院分区：
文献类型：
--
作者：
Iria Maria Prieto Payo;Nutcharin Ongkana;S. Tohno;C. Azuma;T. Minami;Y. Moriwake;Y. Tohno
为了阐明动脉的成分随年龄的变化，作者研究了向收缩器官供血的脾动脉和肺动脉中元素与年龄相关的变化。奈良医科大学医学生完成普通解剖后，受试者的脾动脉和肺动脉被切除，受试者年龄从 58 岁到 94 岁不等。通过电感耦合等离子体原子发射光谱法测定元素含量。研究发现，随着年龄的增长，脾动脉中Ca和P发生中等程度的积累，而肺动脉中几乎不出现Ca和P的积累。关于元素之间的关系，脾动脉和肺动脉中Ca、P、Mg、Na含量普遍存在显着的直接相关性。随着年龄的增长，脾动脉中 Ca 和 P 的积累与肺动脉中的积累无关。组织学观察表明，大部分Ca沉积出现在中膜中，但在内膜中未见。因此，脾动脉发生的钙化属于中度硬化。
To elucidate compositional changes of the arteries with aging, the authors investigated age-related changes of elements in the splenic and pulmonary arteries, which supplied blood to contractile organs. After ordinary dissection by medical students at Nara Medical University was finished, the splenic and pulmonary arteries were resected from the subjects, ranging in age from 58 to 94 years. The element contents were determined by inductively coupled plasma-atomic emission spectrometry. It was found that a moderate accumulation of Ca and P occurred in the splenic artery with aging, but it hardly occurred in the pulmonary artery with aging. Regarding the relationship among elements, the finding that there were significant direct correlations among the contents of Ca, P, Mg, and Na was commonly obtained in both the splenic and pulmonary arteries. The accumulation of Ca and P in the splenic artery with aging occurred independently of that in the pulmonary artery. Histologic observation indicated that a major part of Ca deposits was seen in the middle tunica, but not in the internal tunica. Therefore, the calcification occurring in the splenic artery belonged to middle sclerosis.