A Review of Prognostic Models on Diagnosis and Therapeutic Strategies of Typhoid Fever
A Review of Prognostic Models on Diagnosis and Therapeutic Strategies of Typhoid Fever
复制标题
伤寒诊断和治疗策略的预后模型综述
DOI：
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
V. Nag
中科院分区：
文献类型：
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作者：
K. Abhishek;S. Kombade;V. Nag
背景：甲型副伤寒是一种潜伏性发病的发热和其他一些胃肠道疾病，可能会有致命的后果。病原体为伤寒沙门氏菌、甲型副伤寒沙门氏菌和乙型副伤寒沙门氏菌。临床特征包括逐渐发热，舌白苔色，严重程度不适，嗜睡和腹部疼痛，穿孔并肠道出血，休克和死亡。它主要涉及学龄期的男性受害者。这是一种通过水传播的疾病，由于卫生条件差而传播，主要在人口稠密的地区。根据世界卫生组织的数据，每年报告的伤寒病例为1600万至1700万例，其中60万人死亡。次大陆地区伤寒的发病率是中国的10到29倍。只有当感染者处理食物时，才会发生感染。从疑似病例中分离出的沙门氏菌菌株对常规抗生素表现出抗药性，而现代抗生素要昂贵得多，负担不起。结论：本综述的需要特别是最近研究人员引入的某些类型的真菌制造的银纳米颗粒(AgNPs)，由于其抗菌性能，具有控制或治疗某种感染的优势。在本研究中，这些(AgNPs)以悬浮液的形式，对沙门氏菌物种产生了积极的结果。它使我们能够以一种更便宜的方式治疗伤寒感染。
Background : Typhoid infection is an insidious onset type of fever and some other gastrointestinal disorders which may have a fatal outcome. The causative agents are Salmonella typhi , Salmonella paratyphi A, and Salmonella paratyphi B. Clinical features include, gradual rising fever, white coated tongue, and severe degree of malaise, drowsiness and pain in abdomen, perforation with bleeding in the intestines, shock and death. It involves mostly male victims of school going age. It is water born disease which spreads due to poor sanitation mostly in congested populated areas. According to World Health Organization sixteen to seventeen million typhoid fever cases were reported annually, out of which 600,000 died. Typhoid fever is 10 to 29 times more in subcontinent than China. Infection only occurs when food is handled by infected person. Isolated strains of Salmonella spp from suspected cases show resistance against routine antibiotics and the modern antibiotics are much more expensive and un affordable. Conclusion : Need of this review is especially for Silver Nanoparticles (AgNPs) manufactured by some types of fungi introduced by recent researchers have an edge to control or treat some sort of infections due to their antibacterial properties. In this study these (AgNPs) in the form of suspension, give positive results against the Salmonella species. It enables us to treat the typhoid infection in a less expensive way.
影响因子：
11.8
作者：
Engemann, JJ;Carmeli, Y;Kaye, KS
通讯作者：
Kaye, KS