Microfracture of chondral defects in the knee associated with different results in patients aged 40 years or younger?

Microfracture of chondral defects in the knee associated with different results in patients aged 40 years or younger?
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DOI:
10.1016/j.arthro.2006.06.020
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发表时间:
2006-11-01
影响因子:
4.7
通讯作者:
Suedkamp, Norbert
Suedkamp, Norbert
中科院分区:
医学1区
文献类型:
--
作者:
Kreuz, Peter C.;Erggelet, Christoph;Suedkamp, Norbert

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目的:膝关节软骨损伤微骨折后的临床结果的相关研究仍然缺失。这项前瞻性研究旨在发现微骨折后36个月内结果的年龄依赖性差异。研究方法:在1999年至2002年期间,85例全层软骨病变患者(平均年龄39岁)接受了微骨折手术,并在术前和术后6个月进行了评价。术后18和36个月。根据患者的年龄(40岁)和缺损部位(股骨髁、胫骨和髌股关节),将患者分为6个不同的组。排除标准为踝关节病理状况、胫股排列不良和韧带不稳定。通过使用配对Wilcoxon检验对改良辛辛那提膝关节评分和国际腕关节修复学会(ICRS)评分进行基线临床评分与随访数据进行比较。结果:在整个研究期间,所有组的评分均有所改善(P
Purpose: Age-dependent studies about the clinical result after microfracture of cartilage lesions in the knee are still missing. This prospective study was performed to discover age-dependent differences in the results after microfracture over a period of 36 months. Methods: Between 1999 and 2002, 85 patients (mean age, 39 years) with full-thickness chondral lesions underwent the microfracture procedure and were evaluated preoperatively and at 6. 18, and 36 months after surgery. Depending on the patients' age ( 40 years) and the localization of the defects (femoral condyles, tibia, and patellofemoral joint), the patients were assigned to 6 different groups. Exclusion criteria were meniscal pathologic conditions, tibiofemoral malalignment, and ligament instabilities. Baseline clinical scores were compared with follow-up data by use of paired Wilcoxon tests for the modified Cincinnati knee score and the International Cartilage Repair Society (ICRS) score. Results: The scores improved in all groups over the whole study period (P