Hierarchical Neural Encoding of Temporal Regularity in the Human Auditory Cortex
Hierarchical Neural Encoding of Temporal Regularity in the Human Auditory Cortex
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DOI：
10.1007/s10548-013-0300-3
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发表时间：
2015-05-01
期刊：
影响因子：
2.7
通讯作者：
Kakigi, Ryusuke
中科院分区：
文献类型：
--
作者：
Keceli, Sumru;Okamoto, Hidehiko;Kakigi, Ryusuke
时间规律性为自然声音的识别提供了重要线索。在这里，我们测量听觉诱发的皮层磁场调查的神经处理的时间规律性，不能tonotopically表示在听觉周边。分析了40 Hz调幅周期性和非周期性噪声诱发的听觉稳态反应（ASSR）和持续场（SF）。以重复冻结噪声的形式制备40-、20-和5-Hz的周期性噪声，其中相同的噪声段出现在幅度调制的每个周期（40 Hz）、每隔一个周期（20 Hz）或每隔八个周期（5 Hz）。与非周期性白色噪声相比，重复频率为5-，20-和40-Hz的周期性噪声导致两个半球的SF幅度显着增加。20-和40-Hz周期性噪声在右半球的ASSR振幅显着增强，而在左半球的周期性噪声没有观察到增强。诱发反应成分和半球之间的规律性效应的变化可能反映了ASSR和SF发生器之间以及左右听觉通路之间采用的时间整合窗口长度的差异。
Temporal regularity provides an important cue for the identification of natural sounds. Here, we measured auditory evoked cortical magnetic fields to investigate the neural processing of temporal regularity that cannot be tonotopically represented in the auditory periphery. Auditory steady state responses (ASSR) and sustained fields (SF) elicited by 40 Hz amplitude modulated periodic and non-periodic noises were analyzed. Periodic noises of 40-, 20-, and 5-Hz were prepared in the form of repeating frozen noises where the same noise segment appears at either each period (40 Hz), every second period (20 Hz), or every eighth period (5 Hz) of amplitude modulation. Compared to non-periodic white noises, periodic noises with repetition rates of 5-, 20-, and 40-Hz caused significantly increased SF amplitudes in both hemispheres. ASSR amplitudes were significantly enhanced for 20- and 40-Hz periodic noises in the right hemisphere while no enhancement was observed for periodic noises in the left hemisphere. The observed variation of the regularity effect between evoked response components and hemispheres may reflect the differences in the temporal integration window lengths adopted between ASSR and SF generators and also between the right and left auditory pathways.