Alanine aminotransferase levels among volunteer blood donors: geographic variation and risk factors.
Alanine aminotransferase levels among volunteer blood donors: geographic variation and risk factors.
复制标题
志愿者献血者的丙氨酸转氨酶水平：地理差异和危险因素。
DOI：
10.1093/infdis/145.3.383
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Dodd,RY
中科院分区：
文献类型：
--
作者：
Sherman,KE;Dodd,RY
对美国不同地理区域志愿献血者血清中丙氨酸转氨酶（ALT）水平升高的发生率进行了评估。五个地区采血中心参与其中，随机从志愿献血者中采集样本。血清样本集中检测ALT水平升高，并向ALT水平升高的供者和随机选择的ALT水平正常的供者发送社会人口调查问卷。ALT水平升高的发生率存在显著的区域差异。年龄、性别和饮酒均与ALT水平升高显著相关。这些初步数据对于考虑筛查献血者血清中ALT水平升高的方案是重要的。
The incidence of elevated levels of alanine aminotransferase (ALT) in the serum of volunteer blood donors from different geographic areas of the United States was evaluated. Five regional blood collection centers participated by collecting samples randomly from volunteer blood donors. Serum samples were centrally tested for elevated ALT levels, and a sociodemographic questionnaire was sent to donors with elevated ALT levels and to a randomly selected group with normal levels. Significant regional variation was found in the incidence of elevated ALT levels. Age, sex, and the use of alcohol were all significantly associated with elevated ALT levels. These preliminary data are important in the consideration of a program to screen blood donors for elevated ALT levels in serum.