Pack a STRIPAK with hubs inside a hub.
Pack a STRIPAK with hubs inside a hub.
复制标题
将带座的STRIPAK装入座内。
DOI:
10.1038/s41594-021-00571-z
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发表时间:
2021-03
影响因子:
16.8
通讯作者:
Taylor DJ
中科院分区:
文献类型:
--
作者:
Huang W;Leonard D;Taylor DJ
The highly conserved striatin-interacting phosphatase and kinase (STrIPAK) multimeric complex regulates the hippo signaling pathway through phosphatase activity. A recent structure of the core STrIPAK hub reveals how striatins tetramerize to serve as a scaffolding platform for the assembly of an intricate architecture, which is distinct from that of all other protein phosphatase 2A (PP2A) complexes.
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