Database resources of the National Center for Biotechnology Information
Database resources of the National Center for Biotechnology Information
复制标题
DOI：
10.1093/nar/gku1130
复制
发表时间：
2016-01-04
影响因子：
14.9
通讯作者：
Zbicz, Kerry
中科院分区：
文献类型：
--
作者：
Agarwala, Richa;Barrett, Tanya;Zbicz, Kerry
美国国家生物技术信息中心（NCBI）提供了大量的生物信息和数据的在线资源，包括GenBank（R）核酸序列数据库和PubMed数据库，其中包括已出版的生命科学期刊的引文和摘要。更多NCBI资源聚焦于文献（书架，PubMed Central（PMC）和PubReader）;医学遗传学（ClinVar、dbMHC、遗传检测注册、HIV-1/人类蛋白质相互作用数据库和MedGen）;基因和基因组学（BioProject，BioSample，dbSNP，dbVar，Epigenomics，Gene，Gene Expression Omnibus（GEO），Genome，HomoloGene，the Map Viewer，Nucleotide，PopSet，Probe，RefSeq，Sequence Read Archive，分类浏览器、Trace Archive和UniGene）;以及蛋白质和化学品（Biosystems、COBALT、保守结构域数据库（CDD）、保守结构域结构检索工具（CDART）、分子建模数据库（MMDB）、蛋白质簇、蛋白质和PubChem小分子数据库套件）。该系统为许多这样的数据库提供搜索和检索操作。增强许多Web应用程序是BLAST程序的自定义实现，该程序被优化以搜索专门的数据集。国家生物技术信息中心（NCBI）提供了一套大型的生物信息和数据的在线资源，包括GenBank（R）核酸序列数据库和PubMed数据库，其中包括已出版的生命科学期刊的引文和摘要。更多NCBI资源聚焦于文献（PubMed Central（PMC）、Bookshelf和PubReader）、健康（ClinVar、dbGaP、dbMHC、遗传检测注册、HIV-1/人类蛋白质相互作用数据库和MedGen），基因组（BioProject，Assembly，Genome，BioSample，dbSNP，dbVar，Epigenomics，the Map Viewer，Nucleotide，Probe，RefSeq，Sequence Read Archive，the Taxonomy Browser and the Trace Archive），基因（Gene、Gene Expression Omnibus（GEO）、HomoloGene、PopSet和UniGene）、蛋白质（Protein、Conserved Domain Database（CDD）、COBALT、Conserved Domain Architecture Retrieval Tool（CDART）、Molecular Modeling Database（MMDB）和Protein Clusters）和化学品（Biosystems和PubChem小分子数据库套件）。该系统为大多数这些数据库提供搜索和检索操作。增强许多Web应用程序是BLAST程序的自定义实现，优化为搜索专门的数据集。所有这些资源都可以通过NCBI主页www.ncbi.nlm.nih.gov访问。
The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank (R) nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (Bookshelf, PubMed Central (PMC) and PubReader); medical genetics (ClinVar, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen); genes and genomics (BioProject, BioSample, dbSNP, dbVar, Epigenomics, Gene, Gene Expression Omnibus (GEO), Genome, HomoloGene, the Map Viewer, Nucleotide, PopSet, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser, Trace Archive and UniGene); and proteins and chemicals (Biosystems, COBALT, the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB), Protein Clusters, Protein and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for many of these databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets.The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank (R) nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (PubMed Central (PMC), Bookshelf and PubReader), health (ClinVar, dbGaP, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen), genomes (BioProject, Assembly, Genome, BioSample, dbSNP, dbVar, Epigenomics, the Map Viewer, Nucleotide, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser and the Trace Archive), genes (Gene, Gene Expression Omnibus (GEO), HomoloGene, PopSet and UniGene), proteins (Protein, the Conserved Domain Database (CDD), COBALT, Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB) and Protein Clusters) and chemicals (Biosystems and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for most of these databases. Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized datasets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.