Alcoholism, depression, and abnormal cognition in head and neck cancer: A pilot study
Alcoholism, depression, and abnormal cognition in head and neck cancer: A pilot study
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DOI：
10.1016/j.otohns.2006.06.1275
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发表时间：
2007-01-01
影响因子：
3.4
通讯作者：
Booth-Jones, Margaret
中科院分区：
文献类型：
--
作者：
McCaffrey, Judith Czaja;Weitzner, Michael;Booth-Jones, Margaret
目的：为了确定酒精滥用和依赖，抑郁症和认知障碍的患病率在术前头颈癌patients.Study设计：诊断面试标准化测试被用来确定抑郁症和酒精中毒。Mattis痴呆评定量表检查术前认知能力。24例晚期头颈癌患者参加了研究。研究地点：大学医院。结果：63.6%的患者符合酒精滥用标准，62%的患者符合酒精依赖标准; 26.1%的患者符合重度抑郁标准。在多个认知功能子集的测试表明，酒精依赖者和滥用者都存在可测量的缺陷。所有的赤字是显着的，当与人口normal.CONCLUSIONS：研究结果表明，酗酒，抑郁症和认知障碍的患病率是常见的头颈部癌症患者术前。这些疾病的早期诊断和管理应考虑在头部和颈部癌症患者的护理。(c)2007年美国耳鼻咽喉头颈外科学会基金会。All rights reserved.
OBJECTIVE: To determine prevalence of alcohol abuse and dependency, depression, and cognitive impairment in presurgical head and neck cancer patients.STUDY DESIGN: Standardized testing by diagnostic interview was used to determine major depression and alcoholism. Mattis Dementia Rating Scale examined cognitive ability preoperatively. Twenty-four patients with advanced head and neck cancer participated.SETTING: University hospital.RESULTS: A total of 63.6% met criteria for alcohol abuse and 62 percent for alcohol dependence; 26.1% of patients met criteria for major depression. Testing in multiple subsets of cognitive function demonstrated measurable deficits in both alcohol dependents and abusers. All deficits were significant when compared with population norms.CONCLUSIONS: Findings suggest that prevalence of alcohol abuse, major depression, and cognitive impairment is common in head and neck cancer patients preoperatively. Early diagnosis and management of these disorders should be considered in care of the head and neck cancer patient. (c) 2007 American Academy of Otolaryngology-Head and Neck Surgery Foundation. All rights reserved.