Activation symptoms and discharge in elderly chronic schizophrenic inpatients.
Activation symptoms and discharge in elderly chronic schizophrenic inpatients.
复制标题
老年慢性精神分裂症住院患者的激活症状和出院情况。
DOI：
10.1097/01.nmd.0000146883.74872.07
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Friedman,JosephI
中科院分区：
文献类型：
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作者：
White,Leonard;Opler,LewisA;Harvey,PhilipD;Parrella,Michael;Friedman,JosephI
对333例老年精神分裂症住院患者进行阳性和阴性症状量表（PANSS）评分，并对1年后仍留在医院的患者（N= 267）进行评分并随访一年。基于先前的研究表明，攻击性发作和敌对行为预测无法出院的精神分裂症患者，我们假设，低放电率将与高基线评级的激活因子PANSS（PANSS-AF），通过总结六个项目（敌意，冲动控制差，兴奋，不合作，融洽关系差，紧张）。基线PANSS-AF评分与出院率呈负相关，与其他症状维度评分无关。PANSS-AF评分是一个比任何单个PANSS项目（如敌意）更好的结局预测因子，单个项目评分对出院预测无显著性增加。注意和发展的激活症状，精神分裂症中非常普遍，但不包括在我们目前的诊断系统的治疗，可能会增加老年住院精神分裂症患者转移到社区设置的机会。
Three hundred thirty-three elderly schizophrenic inpatients were rated on the Positive and Negative Syndrome Scale (PANSS), and those remaining in the hospital after 1 year (N= 267) were rated and followed for an additional year. Based on previous studies showing that aggressive episodes and hostile behavior predicted inability to discharge schizophrenics, we hypothesized that low discharge rates would be correlated with high baseline ratings on the activation factor of the PANSS (PANSS-AF), obtained by summing six items (hostility, poor impulse control, excitement, uncooperativeness, poor rapport, and tension). Baseline PANSS-AF scores were found to be inversely correlated with discharge rates, independent of ratings on other symptom dimensions. PANSS-AF scores were a better predictor of outcome than any individual PANSS item (eg, hostility), and individual item scores did not add significantly to prediction of discharge. Attention to and development of treatments for activation symptoms, highly prevalent in schizophrenia but not included in our present diagnostic systems, may increase the chances of elderly inpatients with schizophrenia of moving to community settings.