Trends of admissions and case fatality rates among medical in-patients at a tertiary hospital in Uganda; A four-year retrospective study
Trends of admissions and case fatality rates among medical in-patients at a tertiary hospital in Uganda; A four-year retrospective study
复制标题
DOI：
10.1371/journal.pone.0216060
复制
发表时间：
2019-05-14
期刊：
影响因子：
3.7
通讯作者：
Kamya, Moses R.
中科院分区：
文献类型：
--
作者：
Kalyesubula, Robert;Mutyaba, Innocent;Kamya, Moses R.
背景撒哈拉以南非洲遭受着传染性和非传染性疾病的双重负担。关于内科病房病人入院和死亡的原因和趋势的数据有限。了解发病率和死亡率的主要驱动因素将有助于为卫生系统的改进提供信息。我们确定的原因和趋势的入院和死亡率之间的患者入住Mulago医院，坎帕拉，Uganda.Methods and resultsThe病历数据库的患者入住Mulago医院成人内科病房从2011年1月至2014年12月进行了查询。完成详细的病史、体格检查和检查，以确认诊断并确定合并症。通过苏木精和伊红组织染色进行任何组织病理学诊断。我们确定了10种最常见的住院原因，并使用泊松回归生成年度百分比变化来描述住院原因的趋势。生存期计算从入院之日至死亡之日或出院之日。考克斯生存分析用于确定与住院死亡率相关的因素。我们使用统计学显著性水平p
BackgroundSub-Saharan Africa suffers from a dual burden of infectious and non-communicable diseases. There is limited data on causes and trends of admission and death among patients on the medical wards. Understanding the major drivers of morbidity and mortality would help inform health systems improvements. We determined the causes and trends of admission and mortality among patients admitted to Mulago Hospital, Kampala, Uganda.Methods and resultsThe medical record data base of patients admitted to Mulago Hospital adult medical wards from January 2011 to December 2014 were queried. A detailed history, physical examination and investigations were completed to confirm the diagnosis and identify comorbidities. Any histopathologic diagnoses were made by hematoxylin and eosin tissue staining. We identified the 10 commonest causes of hospitalization, and used Poisson regression to generate annual percentage change to describe the trends in causes of hospitalization. Survival was calculated from the date of admission to the date of death or date of discharge. Cox survival analysis was used to identify factors associate with in-hospital mortality. We used a statistical significance level of p