Application of a locally conservative Galerkin (LCG) method for modelling blood flow through a patient-specific carotid bifurcation
Application of a locally conservative Galerkin (LCG) method for modelling blood flow through a patient-specific carotid bifurcation
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应用局部保守伽辽金 (LCG) 方法对通过患者特异性颈动脉分叉的血流进行建模
DOI：
10.1002/fld.2313
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发表时间：
2010
影响因子：
1.8
通讯作者：
Bevan R
中科院分区：
文献类型：
--
作者：
Bevan R
在目前的工作中，通过患者特定的颈动脉分叉的血流进行了彻底的分析。采用局部守恒的Galerkin空间离散方法，结合人工压缩性和基于特征的分裂格式，沿着求解三维不可压Navier-Stokes方程。引入边界层网格以准确地解析患者特定颈动脉分叉内的高近壁速度梯度。总共有六个血液动力学壁参数被汇集在一起，以分析该区域内可能发生动脉粥样硬化的区域。结果表明，壁面切应力在顶点附近较高（6-15 Pa），沿着有一小部分区域超过20 Pa。该峰值WSS区域靠近颈外动脉（ECA）的内壁。从结果中还可以清楚地看出，低WSS发生在颈总动脉（CCA）中。高振荡剪切发生在CCA远端局部狭窄的颈内动脉和沿着外壁，表明动脉粥样硬化的潜在区域。壁面切应力角偏差和壁面切应力角梯度的最大值出现在顶点处。壁面剪应力的时间梯度达到4000 Pa/s附近的顶点，更接近ECA。壁面剪应力的空间梯度分布与WSS的分布相对应，最大值出现在顶点。版权所有© 2010约翰威利父子有限公司.
In the present work, blood flow through a patient‐specific carotid bifurcation is thoroughly analysed. A locally conservative Galerkin spatial discretization is applied along with an artificial compressibility and characteristic‐based split scheme to solve the 3D incompressible Navier–Stokes equations. Boundary layer meshes are introduced to accurately resolve high near‐wall velocity gradients inside a patient‐specific carotid bifurcation. A total of six haemodynamic wall parameters have been brought together to analyse the regions of possible atherogenesis within the domain. The results show that wall shear stress (WSS) is high (6–15 Pa) near the apex, along with a small region where WSS exceeded 20 Pa. This peak WSS region is close to the inner wall of the external carotid artery (ECA). It is also clear from the results that low WSS occurred in the common carotid artery (CCA). High oscillatory shear occurred in the CCA distal to a local narrowing of the internal carotid artery and along the outer wall, indicating a potential region of atherogenesis. The highest values of wall shear stress angle deviation and wall shear stress angle gradient occur at the apex. The wall shear stress temporal gradient reached 4000 Pa/s near the apex, closer to the ECA. Wall shear stress spatial gradient distribution corresponded with the WSS distribution, with a maximum occurring at the apex. Copyright © 2010 John Wiley & Sons, Ltd.