Effect of manual acupuncture on bowel motility in normal kunming mouse.
Effect of manual acupuncture on bowel motility in normal kunming mouse.
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DOI：
10.1016/s0254-6272(15)30033-9
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发表时间：
2015-04
期刊：
影响因子：
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通讯作者：
Zhao Yuxue;Cui Changxiang;Q. Qingguang;Ben Hui;G. Jun-hong;Yuan Xiaochun;Z. Bing
中科院分区：
文献类型：
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作者：
Zhao Yuxue;Cui Changxiang;Q. Qingguang;Ben Hui;G. Jun-hong;Yuan Xiaochun;Z. Bing
目的观察针刺不同穴位对正常昆明小鼠空肠和远端结肠运动的影响。方法采用肠内囊记录40只昆明小鼠的空肠和结直肠运动活动。将含有蒸馏水的胶囊放入空肠和远端结肠的腔内。将肠道的变化与任何刺激之前记录的背景活动进行比较。所选穴位如下：小腿足三里（ST 36），中下腹部天枢（ST 25）。结果手针足三里（ST 36）显着促进正常昆明小鼠空肠和远端结肠的蠕动（表现为平均振幅变化率增加和收缩曲线下平均面积变化率增加） （P<0.01）。天枢MA（ST 25）显着抑制正常昆明小鼠空肠蠕动（表现为平均振幅变化率降低、收缩曲线下面积变化率降低、频率降低）（P<0.01），而显着增加正常昆明小鼠远端结肠蠕动（表现为振幅增大、收缩曲线下平均面积增大）（P<0.01）。 0.01).结论MA特定穴位[足三里(ST 36)、天枢(ST 25)]对空肠和远端结肠的运动有不同的影响，可能涉及相关神经的节段神经支配。
ObjectiveTo observe the effects of acupuncture on motility of jejunum and distal colon at different acupoints on normal Kunming mice.MethodsThe jejunal and colorectal motor activity of forty Kunming mice were recorded by the intra-intestinal capsule. The capsules contained with distilled water were placed into the cavities of jejunum and distal colon. The changes of bowel were compared with the background activity recorded before any stimulation. The chosen acupoints were as follows: Zusanli (ST 36) on the lower legs, Tianshu (ST 25) on the mid-lower abdomen.ResultsManual acupuncture (MA) at Zusanli (ST 36) significantly promoted the motility of jejunum and distal colon (manifested as increased change rate of average amplitude and increased change rate of mean area under the contractile curve) of normal Kunming mice (P< 0.01). MA at Tianshu (ST 25) significantly inhibited the motility of jejunum (manifested as decreased change rate of average amplitude, decreased change rate of mean area under the contractile curve, and the reduced frequency) of normal Kunming mice (P< 0.01), while significantly increased the distal colonic motility (manifested as increased amplitude and increased mean area under the contractile curve) of normal Kunming mice (P< 0.01).ConclusionMA at specific acupoints [Zusanli (ST 36), Tianshu (ST 25)] has different effects on the motility of jejunum and distal colon, which might involve the segmental innervations of the related nerve.