Polypharmacy and Delirium in Critically Ill Older Adults Recognition and Prevention
Polypharmacy and Delirium in Critically Ill Older Adults Recognition and Prevention
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DOI：
10.1016/j.cger.2017.01.002
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发表时间：
2017-05-01
影响因子：
3.3
通讯作者：
Devlin, John W.
中科院分区：
文献类型：
--
作者：
Garpestad, Erik;Devlin, John W.
在老年人中，多种药物治疗是进入重症监护室的后遗症，与药物相关不良事件、药物相互作用和医疗保健费用增加有关。谵妄在重症老年患者中很普遍，药物治疗在这种情况下仍然是一种未被充分认识的谵妄可改变风险。本文回顾了多药和谵妄的文献，重点突出了重症，老年人多药和谵妄之间的关系。讨论了临床医生的策略，如何识别和减少药物相关的谵妄和建议，有助于防止多药治疗时，干预措施，以减少谵妄的负担，在这个弱势群体正在制定。
Among older adults, polypharmacy is a sequelae of admission to the intensive care unit and is associated with increased medication-associated adverse events, drug interactions, and health care costs. Delirium is prevalent in critically ill geriatric patients and medications remain an underappreciated modifiable risk for delirium in this setting. This article reviews the literature on polypharmacy and delirium, with a focus on highlighting the relationships between polypharmacy and delirium in critically ill, older adults. Discussed are clinician strategies on how to recognize and reduce medication-associated delirium and recommendations that help prevent polypharmacy when interventions to reduce the burden of delirium in this vulnerable population are being formulated.