Consistency With the DASH Diet and Incidence of Heart Failure
Consistency With the DASH Diet and Incidence of Heart Failure
复制标题
DOI：
10.1001/archinternmed.2009.56
复制
发表时间：
2009-05-11
影响因子：
--
通讯作者：
Mittleman, Murray A.
中科院分区：
文献类型：
--
作者：
Levitan, Emily B.;Wolk, Alicja;Mittleman, Murray A.
背景：DASH （Dietary Approaches to Stop Hypertension）饮食能有效降低血压。在观察性研究中，研究了符合DASH的饮食与冠心病和中风风险之间的关系，并得出了不同的结果。我们假设符合DASH饮食的饮食与较低的心力衰竭（HF）发生率相关。方法：我们在瑞典乳房x线摄影队列中对36 019名参与者进行了一项前瞻性观察研究，这些参与者年龄在48至83岁之间，无基线HF、糖尿病或心肌梗死。饮食使用食物频率问卷进行测量。我们创建了一个分数，通过对DASH饮食成分的摄入量进行排名来评估与DASH饮食的一致性，并根据食物和营养指南创建了3个额外的分数。利用1998年1月1日至2004年12月31日期间瑞典住院患者和死因登记资料，采用Cox比例风险模型计算hf相关住院或死亡的比率。结果：在7年中，443名妇女发生HF。在调整了年龄、体力活动、能量摄入、教育状况、心肌梗死家族史、吸烟、绝经后激素使用、独居、高血压、高胆固醇浓度、体重指数（以体重公斤除以身高平方米计算）和心肌梗死发生率后，DASH饮食评分最高的四分之一女性的心衰发生率降低了37%。四分位数间的比率（95%置信区间）分别为1、0.85（0.66-1.11）、0.69（0.54-0.88）和0.63 (0.48-0.81)；P-trend < .001。基于指导线的评分也出现了类似的模式。结论：在该人群中，符合DASH饮食的饮食与较低的心衰发生率相关。
Background: The Dietary Approaches to Stop Hypertension (DASH) diet effectively reduces blood pressure. In observational studies, the association between diets consistent with DASH and risk of coronary heart disease and stroke has been examined with varying results. We hypothesized that diets consistent with the DASH diet would be associated with a lower incidence of heart failure (HF).Methods: We conducted a prospective observational study in 36 019 participants in the Swedish Mammography Cohort who were aged 48 to 83 years and without baseline HF, diabetes mellitus, or myocardial infarction. Diet was measured using food-frequency questionnaires. We created a score to assess consistency with the DASH diet by ranking the intake of DASH diet components and 3 additional scores based on food and nutrient guidelines. Cox proportional hazards models were used to calculate rate ratios of HF-associated hospitalization or death, determined using the Swedish inpatient and cause-of-death registers between January 1, 1998, and December 31, 2004.Results: During 7 years, 443 women developed HF. Women in the top quartile of the DASH diet score based on ranking DASH diet components had a 37% lower rate of HF after adjustment for age, physical activity, energy intake, education status, family history of myocardial infarction, cigarette smoking, postmenopausal hormone use, living alone, hypertension, high cholesterol concentration, body mass index ( calculated as weight in kilograms divided by height in meters squared), and incident myocardial infarction. Rate ratios (95% confidence intervals) across quartiles were 1 [Reference], 0.85 (0.66-1.11), 0.69 (0.54-0.88), and 0.63 (0.48-0.81); P-trend < .001. A similar pattern was seen for the guide-line-based scores.Conclusion: In this population, diets consistent with the DASH diet are associated with lower rates of HF.