Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease: an investigation into “re-build-up” on EEG by positron CT

Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease: an investigation into “re-build-up” on EEG by positron CT
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儿童烟雾病脑血流和代谢的评估:正电子CT脑电图“重建”的研究

DOI:
10.1007/bf00270840
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发表时间:
1986
期刊:
Child's Nervous System
影响因子:
--
通讯作者:
T. Ido
T. Ido
中科院分区:
--
文献类型:
--
作者:
M. Kameyama;R. Shirane;Y. Tsurumi;A. Takahashi;S. Fujiwara;J. Suzuki;Masatoshi Ito;T. Ido

文献摘要

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采用正电子发射计算机断层扫描检测3例儿童烟雾病患者脑血流量、脑氧代谢率(CBF)和cro2,探讨脑电图“重建”现象的机制。过度通气后CBF和cro2均下降。然而,也观察到CBF减少和cro2之间的解离。动脉血气分析显示过度通气时低呼吸和过度通气后缺氧。这些结果清楚地表明,脑电图上的重建不仅是缺血性缺氧的表现,也是烟雾病所特有的缺氧的表现。
The cerebral blood flow and cerebral metabolic rate of oxygen (CBF and CMRO2) of three cases of childhood moyamoya disease were examined by positron-emission-computed tomography for the purpose of investigating the mechanism of the “re-build-up” phenomenon on EEG. Decrease in both CBF and CMRO2were observed following hyperventilation. However, dissociation between the decrease in CBF and CMRO2was also observed. Arterial blood-gas analysis disclosed hypocapnea during hyperventilation and hypoxia following hyperventilation. These results clearly indicate that the re-build-up seen on EEG is the manifestation not only of ischemic hypoxia but also of hypoxic hypoxia characteristically seen in moyamoya disease.