Disentangling the overlap between Tourette's disorder and ADHD
Disentangling the overlap between Tourette's disorder and ADHD
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DOI：
10.1111/1469-7610.00406
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发表时间：
1998-10-01
影响因子：
7.6
通讯作者：
Geller, D
中科院分区：
文献类型：
--
作者：
Spencer, T;Biederman, J;Geller, D
目的：探讨抽动秽语综合征(TS)和注意缺陷多动障碍(ADHD)儿童神经精神病学相关因素的异同。方法：Tourette综合征伴ADHD患儿79例，Tourette综合征伴ADHD患儿18例，ADHD患儿563例，精神咨询患儿212例，健康对照组140例。结果：与多发性抽动症相关的疾病有强迫症和单纯性恐惧症。其他障碍的发生率，包括其他破坏性行为、情绪和焦虑障碍，神经心理学相关因素，以及社会和学校功能在抽动症和ADHD儿童中是无法区分的。然而，与ADHD儿童相比，Tourette综合征合并ADHD的儿童总体上有更多的额外共病障碍和更低的心理社会功能。结论：这些发现证实了先前提到的多发性抽动症和强迫症之间的联系，但也表明破坏性的行为、情绪、焦虑障碍以及认知功能障碍可能与ADHD的共病有关。然而，Tourette综合征合并ADHD似乎比单独ADHD更严重。
Objective: To identify similarities and differences in neuropsychiatric correlates in children with Tourette's syndrome (TS) and those with ADHD. Method: The sample consisted of children with Tourette's syndrome with ADHD (N = 79), children with Tourette's syndrome without ADHD (N = 18), children with ADHD (N = 563), psychiatrically referred children (N = 212), and healthy controls (N = 140). Results: Disorders specifically associated with Tourette's syndrome were obsessive compulsive disorder (OCD) and simple phobias. Rates of other disorders, including other disruptive behavioral, mood, and anxiety disorders, neuropsychologic correlates, and social and school functioning were indistinguishable in children with Tourette's and ADHD. However, children with Tourette's syndrome plus ADHD had more additional comorbid disorders overall and lower psychosocial function than children with ADHD. Conclusions: These findings confirm previously noted associations between Tourette's syndrome and OCD but suggest that disruptive behavioral, mood, and anxiety disorders as well as cognitive dysfunctions may be accounted for by comorbidity with ADHD. However, Tourette's syndrome plus ADHD appears to be a more severe condition than ADHD alone.