Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice
Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice
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DOI：
10.1080/10286020412331286425
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发表时间：
2006-12
影响因子：
1.7
通讯作者：
Xin-Bao Yang;Hui Zhang;Ming Li;Lijun Du;Z. Yang;Shi-ying Xiao
中科院分区：
文献类型：
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作者：
Xin-Bao Yang;Hui Zhang;Ming Li;Lijun Du;Z. Yang;Shi-ying Xiao
从吴茱萸 (Evodia rutaecarpa (Juss) Benth var.) 的果实中分离出六种生物碱 (1–6)。 bodinaieri (Dode) Huang，其中两个是新化合物，被鉴定为2-十一烷基-4(1H)-喹诺酮(4)和1-甲基-2-十一烷酮-10'-4(1H)-喹诺酮(5)；已知化合物被鉴定为吴茱萸碱 (1)、吴茱萸碱 (2)、1-甲基-2-十一烷基-4(1H)-喹啉 (3) 和 2-十一烷酮-10'-4(1H)-喹诺酮 (6)。评估了化合物 1-5 的急性毒性。
Six alkaloids (1–6) have been isolated from the fruits of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang, two of which are new compounds, identified as 2-undecyl-4(1H)-quinolone (4) and 1-methyl-2-undecanone-10′-4(1H)-quinolone (5); the known compounds were identified as rutaecarpine (1), evodiamine (2), 1-methyl-2-undecyl-4(1H)-quinoline (3) and 2-undecanone-10′-4(1H)-quinolone (6). Compounds 1–5 were evaluated for their acute toxicity.