Effect on the canine Eck fistula liver of intraportal TGF‐β alone or with hepatic growth factors
Effect on the canine Eck fistula liver of intraportal TGF‐β alone or with hepatic growth factors
复制标题
单独使用门静脉内TGF-β或联合肝生长因子对犬Eck瘘肝脏的影响
作者：
A. Francavilla;A. Azzarone;G. Carrieri;Carlo Scotti‐Fogueni;Q. Zeng;U. Cillo;K. Porter;T. Starzl
Transforming growth factor‐β canceled the hepatocyte proliferation caused by transforming growth factor‐α when the two substances were mixed and administered through a disconnected central portal vein branch after creation of an Eck fistula. In contrast, transforming growth factor‐β had no antidotal action on the stimulatory effects of insulin or full test doses of insulinlike factor‐2, hepatocyte growth factor, epidermal growth factor or triiodothymanine. A minor antidotal effect on hepatic stimulatory substance activity could be detected, but only with hepatic stimulatory substance was given in doses smaller than those known to cause maximum stimulatory response. These results suggest a highly specific pharmacological and physiological interaction between transforming growth factor‐α and transforming growth factor‐α in the modulation of liver growth control. (HEPATOLOGY 1992;16:1267–1270.)
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两种血清因子控制肝细胞复制。
影响因子：
11.2
作者：
Michalopoulos,G;Houck,KA;Dolan,ML;Leutteke,NC
通讯作者：
Leutteke,NC
DOI：
10.1073/pnas.85.5.1539
发表时间：
1988-03-01
影响因子：
11.1
作者：
BRAUN, L;MEAD, JE;FAUSTO, N
通讯作者：
FAUSTO, N
人 FKBP（FK506 和雷帕霉素的结合蛋白）对狗的保肝特性。
影响因子：
6.2
作者：
Starzl,TE;Schreiber,SL;Albers,MW;Porter,KA;Foglieni,CS;Francavilla,A
通讯作者：
Francavilla,A
影响因子：
11.2
作者：
A. Francavilla;P. Ove;L. Polimeno;M. Coetzee;L. Makowka;J. Rose;D. V. Van Thiel;T. Starzl
通讯作者：
A. Francavilla;P. Ove;L. Polimeno;M. Coetzee;L. Makowka;J. Rose;D. V. Van Thiel;T. Starzl
大鼠部分肝切除术后肝脏再生中的转化生长因子受体。
影响因子：
11.2
作者：
Gruppuso,PA;Mead,JE;Fausto,N
通讯作者：
Fausto,N