Clinical Repetitive Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder, Generalized Anxiety Disorder, and Bipolar Disorder

Clinical Repetitive Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder, Generalized Anxiety Disorder, and Bipolar Disorder
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DOI:
10.1016/j.psc.2018.04.007
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发表时间:
2018-09-01
影响因子:
1.7
通讯作者:
Kozel, F. Andrew
Kozel, F. Andrew
中科院分区:
医学3区
文献类型:
--
作者:
Kozel, F. Andrew

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重复经颅磁刺激(rTMS)正在研究精神疾病,如创伤后应激障碍(PTSD),广泛性焦虑症(GAD),和双相情感障碍的两个阶段。病例系列、开放性试验和随机对照研究已经初步证实了单独使用rTMS以及rTMS联合心理治疗治疗PTSD的可行性。同样,有一些证据表明GAD可以用rTMS治疗。治疗双相情感障碍的结果是混合的,目前的大多数研究显示缺乏比假的好处。在推荐rTMS用于这些疾病之前,需要进一步研究。
Repetitive transcranial magnetic stimulation (rTMS) is being investigated for psychiatric disorders, such as posttraumatic stress disorder (PTSD), generalized anxiety disorder (GAD), and both phases of bipolar disorder. Case series, open trials, and randomized controlled studies have demonstrated preliminary support for treating PTSD with rTMS alone as well as with rTMS combined with psychotherapy. Similarly, there is some evidence that GAD can be treated with rTMS. The results for treating either phase of bipolar disorder are mixed, with most of the current studies showing lack of benefit over sham. Further study is required before rTMS can be recommended for these disorders.