Application of Nanomaterials in Regulating the Fate of Adipose-derived Stem Cells.
Application of Nanomaterials in Regulating the Fate of Adipose-derived Stem Cells.
复制标题
纳米材料在调节脂肪干细胞命运中的应用。
DOI：
10.2174/1574888x15666200502000343
复制
发表时间：
2020-05
影响因子：
2.7
通讯作者：
Jingang Xiao
中科院分区：
文献类型：
--
作者：
Lang Wang;Yong Li;Maorui Zhang;Kui Huang;Shuanglin Peng;Jingang Xiao
脂肪干细胞是一种容易获得、多能的成体干细胞。干细胞治疗已成为治疗多种疾病的一种有前景的新疗法，并在组织修复、再生和重建领域发挥着越来越重要的作用。细胞外微环境的物理化学性质有助于调节干细胞的命运。纳米材料具有稳定的粒径、较大的比表面积和良好的生物相容性，在生物医学领域具有广阔的应用前景。本文综述了纳米材料在脂肪干细胞研究中的最新进展。综上所述，目前的文献表明，纳米材料可以调节脂肪干细胞的增殖和分化。然而，纳米材料的性质和调节效果可能会因其组成而有很大不同。这篇综述旨在为未来干细胞研究纳米材料的使用提供一个全面的指导。
Adipose-derived stem cells are adult stem cells which are easy to obtain and multi-potent. Stem-cell therapy has become a promising new treatment for many diseases, and plays an increasingly important role in the field of tissue repair, regeneration and reconstruction. The physicochemical properties of the extracellular microenvironment contributes to regulation of the fate of stem cells. Nanomaterials have stable particle size, large specific surface area and good biocompatibility, which has led to them being recognized as having broad application prospects in the field of biomedicine. In this paper, we review recent developments of nanomaterials in adipose-derived stem cell research. Taken together, the current literature indicates that nanomaterials can regulate the proliferation and differentiation of adipose-derived stem cells. However, the properties and regulatory effects of nanomaterials can vary widely depending on their composition. This review aims to provide a comprehensive guide for future stem-cell research on the use of nanomaterials.