[Hepatitis C in hemodialysis patients].
[Hepatitis C in hemodialysis patients].
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发表时间：
2001-07
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通讯作者：
M. Miyano;H. Tanaka;S. Ishitani
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作者：
M. Miyano;H. Tanaka;S. Ishitani
对99例血液透析患者慢性丙型肝炎的特点进行了分析。18例抗-HCV阳性患者中11例（61.1%）HCV-RNA阳性，81例抗-HCV阴性患者中13例（16.0%）HCV-RNA阳性。24例HCV-RNA阳性患者根据抗-HCV阳性分为2组。抗-HCV阳性组11例中有7例HCV感染超过100 K拷贝/ml，抗-HCV阴性组13例中有1例HCV感染超过100 K拷贝/ml。抗-HCV阳性组HCV-RNA拷贝数明显增多。14例血液透析中的活检和尸检，组织学诊断与慢性丙型肝炎的临床特征不相符。
Characteristics of chronic hepatitis C in 99 hemodialysis patients were studied. Eleven out of 18 anti-HCV-positive patients(61.1%) and 13 out of 81 anti-HCV-negative patients (16.0%) were HCV-RNA-positive. Twenty four HCV-RNA-positive patients were divided into 2 groups according to anti-HCV-positivity. Seven out of 11 patients in anti-HCV-positive group and 1 out of 13 in anti-HCV-negative group were infected with more than 100 K copies/ml of HCV. A number of HCV-RNA copy was significantly larger in anti-HCV-positive group. Fourteen biopsies and necropsies in hemodialysis were achieved and the histological diagnosis did not correspond to clinical feature of chronic hepatitis C.