STRUCTURE OF THE RECEPTIVE-FIELDS OF BIPOLAR CELLS IN THE SALAMANDER RETINA
STRUCTURE OF THE RECEPTIVE-FIELDS OF BIPOLAR CELLS IN THE SALAMANDER RETINA
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DOI：
10.1152/jn.1987.58.6.1275
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发表时间：
1987-12-01
影响因子：
2.5
通讯作者：
WILSON, M
中科院分区：
文献类型：
--
作者：
BORGES, S;WILSON, M
1.用暗适应眼离体视网膜研究了蝾螈视网膜双极细胞的感受野结构。2.感受野标测用直径为25微米的光斑进行，光斑的波长和强度旨在刺激视杆细胞而不是视锥细胞。3.超极化和去极化双极细胞的感受野有一个单一的中心点的最大灵敏度，从敏感性呈放射状下降。对抗性的包围无法用一个小光点来证明。4.发现感受野的直径在374和662微米之间变化，与单个双极细胞有效地连接到323- 1，275个杆相一致。5.荧光黄注射双极细胞显示树突状乔木的最大尺寸在43和70微米之间变化，与每个双极细胞的10和24个杆之间的直接突触连接一致。6.我们排除信号传播杆网络内，广泛的横向分支杆过程，突触传递的非线性，和光散射，作为可能的解释大双极细胞感受野。相反，信号很可能在双极细胞之间广泛共享。
1. The receptive-field structure of bipolar cells in the salamander retina has been examined using isolated retinae from dark-adapted eyes. 2. Receptive-field mapping was carried out with a 25-microns diam spot of light whose wavelength and intensity was intended to stimulate rods rather than cones. 3. Both hyperpolarizing and depolarizing bipolar cells showed receptive fields having a single central point of maximum sensitivity from which sensitivity declined radially. Antagonistic surrounds could not be demonstrated using a small spot of light. 4. The diameter of receptive fields was found to vary between 374 and 662 micron, consistent with a single bipolar cell being effectively connected to 323-1,275 rods. 5. Lucifer yellow injections of bipolar cells revealed dendritic arbors whose greatest dimensions varied between 43 and 70 microns, consistent with a direct synaptic connection of between 10 and 24 rods to each bipolar cell. 6. We rule out signal spread within the rod network, extensive lateral ramification of rod process, nonlinearity of synaptic transmission, and light scatter, as possible explanations of large bipolar cell receptive fields. It seems likely, instead, that signals are extensively shared between bipolar cells.