A refinement and coarsening indicator algorithm for finding sparse solutions of inverse problems
A refinement and coarsening indicator algorithm for finding sparse solutions of inverse problems
复制标题
一种寻找逆问题稀疏解的细化和粗化指标算法
DOI:
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发表时间:
2011
期刊:
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通讯作者:
Jonas Offtermatt
中科院分区:
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作者:
B. Kaltenbacher;Jonas Offtermatt
In this paper we extend the idea of adaptive discretization by using refinement and coarsening indicators from papers by Chavent, Bissell, Benameur and Jaffre (cf., e.g., [5], [9]) to a general setting. This allows to make use of the relation between adaptive discretization and sparse paramerization in order to construct an algorithm for finding sparse solutions of inverse problems.
We provide some first steps in the analysis of the proposed method and apply it to an inverse problem in systems biology, namely the reconstruction of gene networks in an ordinary differential equation (ODE) model. Here due to the fact that not all genes interact with each other, reconstruction of a sparse connectivity matrix is a key issue.