Diagnostic accuracy of urine filtration and dipstick tests for Schistosoma haematobium infection in a lightly infected population of Ghanaian schoolchildren
Diagnostic accuracy of urine filtration and dipstick tests for Schistosoma haematobium infection in a lightly infected population of Ghanaian schoolchildren
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DOI：
10.1016/j.actatropica.2011.02.006
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发表时间：
2011-05-01
期刊：
影响因子：
2.7
通讯作者：
Gute, David M.
中科院分区：
文献类型：
--
作者：
Kosinski, Karen C.;Bosompem, Kwabena M.;Gute, David M.
对血尿试剂试纸法和血吸虫虫卵尿滤法两种筛查方法诊断轻度感染加纳儿童血吸虫感染的敏感性和特异性进行了评价。8-18岁学龄儿童(n=255)三次提供尿样。总体而言，36.4%的女孩和50.7%的男孩至少出现一次鸡蛋；3.3%的女孩和7.5%的男孩同时出现鸡蛋和血尿三次。许多儿童有鸡蛋但没有血尿，或有血尿但没有鸡蛋。当每名儿童进行三次筛查时，每种检测方法的敏感度都比单一筛查至少提高了22.9%，但在第三次筛查时发现了以前未确认的感染，这表明即使三次筛查也是不够的。近一半的轻度感染儿童(
Two screening methods, reagent dipsticks for hematuria and urine filtration for Schistosoma haematobium eggs, were evaluated for their sensitivity and specificity in diagnosing infection with S. haematobium in lightly infected Ghanaian children. Schoolchildren aged 8-18 years (n = 255) provided urine samples on three occasions. Overall, 36.4% of girls and 50.7% of boys presented with eggs at least once; 3.3% of girls and 7.5% of boys presented with both eggs and hematuria three times. Many children presented with eggs but without hematuria, or with hematuria but without eggs. When each child was screened three times, the sensitivity of each test method improved by at least 22.9% as compared with single screening, but previously unidentified infections were detected at the third screening, indicating that even three screenings is insufficient. Nearly half of lightly infected children (