EXPERIMENTAL ASSESSMENT OF PHASED-ARRAY HEATING OF NECK TUMORS

EXPERIMENTAL ASSESSMENT OF PHASED-ARRAY HEATING OF NECK TUMORS
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DOI:
10.3109/02656739009141151
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发表时间:
1990-03-01
影响因子:
3.1
通讯作者:
LUMORI, MLD
LUMORI, MLD
中科院分区:
医学2区
文献类型:
--
作者:
GROSS, EJ;CETAS, TC;LUMORI, MLD

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相控阵微波系统(PAMS)的非侵入性诱导热疗,主要是在颈部病变的调查,已经完成了与其他网站,如肺和骨盆的应用程序的影响。我们的一般方法是将联合收割机的数值和分析方法与平行的实验研究相结合。在本文中,我们将只集中在实验方面。该对象,如均匀的圆柱体模或颈部体模,被包围由一个单一的源驱动的几个标准的施加器,但与相对相位和振幅控制每个施加器。通过使用连接到HP网络分析仪的植入式天线来调整施加器的相对相位。施加功率,并通过使用分割体模和热成像法或通过测量植入温度计探头记录的温度瞬变dT/dt来确定比吸收率(SAR)。我们发现,在915 MHz时,我们的施源器(SMA Co.)直径为11 cm的肌肉状体模的中心被加热到施加器前方表面处的值的约33%。同样,我们能够显示显着的SAR在中心的实际尺寸的颈部幻影使用四个相控孔径915 MHz。此外,如果频率降低到约400 MHz,则观察到显著的改善。
An investigation of phased-array microwave systems (PAMS) for non-invasively inducing hyperthermia, primarily in neck lesions, has been done with implication for applications at other sites such as lung and pelvis. Our general approach was to combine numerical and analytical approaches with parallel experimental studies. In this paper we will concentrate only on the experimental aspects. The object, such as a homogeneous cylindrical phantom or a neck phantom, was encircled with several standard applicators driven by a single source, but with relative phase and amplitude control over each applicator. The relative phases of the applicators were adjusted by using an implanted monopole antenna connected to an HP network analyser. Power was applied and the specific absorption rate (SAR) was determined by using split phantoms and thermography or by measuring temperature transients dT/dt, recorded by implanted thermometer probes. We found that at 915 MHz for our applicators (SMA Co.) the centre of an 11 cm diameter muscle-like phantom heated to about 33% of the value at the surface in front of the applicator. Similarly, we were able to show significant SAR at the centre of realistically sized neck phantoms using four phased apertures of 915 MHz. Furthermore, substantial improvement was observed if the frequency was lowered to about 400 MHz.