EXERCISE AND IMMUNOLOGY
EXERCISE AND IMMUNOLOGY
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DOI：
10.1249/00005768-199402000-00001
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发表时间：
1994-02-01
期刊：
影响因子：
--
通讯作者：
NASH, MS
中科院分区：
文献类型：
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作者：
NASH, MS
体力活动对宿主防御影响的记录可以追溯到 1900 年代初，尽管运动对健康人传染病和肿瘤疾病易感性的影响长期以来一直存在广泛的分歧。对于已经易患或受免疫疾病或功能障碍困扰的人来说，运动对于降低疾病倾向的作用知之甚少。然而，最近的报告表明，运动可以降低感染的发生率和严重程度。这些报告得到了良好的流行病学和实验室研究的支持，这些研究表明适度运动与增强免疫功能或降低疾病发病率之间存在联系，而在过度运动的情况下，这种关系会相反。本次研讨会将介绍有关运动对免疫功能和疾病易感性的有益和有害影响的最新信息。作者将强调急性运动和体育训练对免疫细胞及其神经内分泌/免疫调节剂的直接影响。将强调运动、感染易感性和免疫系统功能之间的关系，以及运动诱导的自然杀伤细胞激活和疾病/疾病调节。针对患有肿瘤、自主神经功能障碍、衰老相关免疫衰老和艾滋病的患者，将讨论运动对免疫功能和疾病进展的影响。
The documented effects of physical activity on host defense date to the early 1900s, although the influences of exercise on infectious and neoplastic disease susceptibility in healthy persons have long been subject to widespread disagreement. Even less is known of the effects of exercise in reducing illness predilection for persons already susceptible to, or afflicted,by, immune disease or dysfunction. Recently, however, reports suggest that exercise may reduce the incidence and severity of infection. These reports have been bolstered by well-conducted epidemiologic and laboratory studies demonstrating a link between moderate exercise and either heightened immune function or reduced disease incidence, a relationship that is reversed in instances of immoderate exercise. This symposium will present current information addressing beneficial and detrimental influences of exercise on immune function and disease susceptibility. The authors will emphasize direct effects of acute exercise and physical training on immune cells and their neuroendocrine/immune modulators. The relationship among exercise, infection susceptibility, and immune system function will be highlighted, as well as exercise-induced activation of, and illness/disease regulation by, natural killer cells. Consequences of exercise on immune function and disease advancement will be addressed for persons with neoplasia, autonomic dysfunction, aging-related immunosenescence, and AIDS.