Measuring rodent electroretinograms to assess retinal function.
Measuring rodent electroretinograms to assess retinal function.
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DOI：
10.1007/978-1-61779-848-1_19
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发表时间：
2012-01-01
期刊：
影响因子：
--
通讯作者：
Kraft, Timothy W
中科院分区：
文献类型：
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作者：
Clark, Molly E;Kraft, Timothy W
视网膜电图是一种非侵入性技术，用于测量视网膜神经元的电活动。视网膜电图（ERG）波形可以用来量化正常和患病啮齿动物的视网膜功能。特别是，杆状和锥状通路的功能可以被分离。视网膜内神经元功能，如双极细胞活动或神经节细胞活动，也可以测量。在本章中，我们描述了用于分离和比较杆驱动和锥驱动函数的常见的全视场ERG技术，包括scoptic flash， photopic flash和flicker。
Electroretinography is a noninvasive technique used to measure the electrical activity of neurons in the retina. Electroretinogram (ERG) waveforms can be used to quantify retinal function in normal and diseased rodents. In particular, the functions of rod and cone pathways can be isolated. Inner retinal neuronal functioning, such as bipolar cell activity or ganglion cell activity, can also be measured. In this chapter we describe the common full-field ERG techniques of scoptic flash, photopic flash, and flicker used to isolate and compare rod-driven and cone-driven function.