Polymorphism of Compound Existing as Both Racemic Compound Crystals and Mixed Crystals of Enantiomers
Polymorphism of Compound Existing as Both Racemic Compound Crystals and Mixed Crystals of Enantiomers
复制标题
外消旋化合物晶体和对映体混晶存在的化合物多晶型现象
DOI：
10.1080/10587259608039383
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发表时间：
1996
影响因子：
0.7
通讯作者：
K. Kobayashi
中科院分区：
文献类型：
--
作者：
T. Ushio;R. Tamura;N. Azuma;Kimitaka Nakamura;F. Toda;K. Kobayashi
通过外消旋化合物(ST)的重结晶，得到外消旋化合物晶体、两种对映体的混合晶体或这两种类型的晶体的混合物，具体取决于重结晶条件。通过单晶和粉末材料的X-射线衍射法确定了它们的晶型。混合晶体的空间群和晶格参数与对映体晶体的空间群和晶格参数一致。ST晶体的这种多型性可以归因于对映体晶体和外消旋晶体热力学稳定性的微小差异。文中还对ST的物化性质进行了描述。
Abstract By recrystallization of certain racemic compound (ST), racemic compound crystals, mixed crystals of two enantiomers, or a mixture of these two types of crystals were obtained, depending on the recrystallization conditions employed. Their crystal forms were determined by X-ray diffraction of the single crystals and powdered materials. The space group and lattice parameters of the mixed crystals were identical with those of the enantiomeric crystals. This polymorphism of ST crystals would be ascribed to the small difference in the thermodynamic stability between the enantiomeric and racemic crystals. The physicochemical properties of ST are described, too.