Nasal Schneiderian papillomas: a study of 83 cases.
Nasal Schneiderian papillomas: a study of 83 cases.
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鼻施奈德乳头状瘤：83 例研究。
DOI：
10.1111/j.1365-2273.1985.tb01181.x
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
H. Søgaard
中科院分区：
文献类型：
--
作者：
S. Kristensen;P. Vorre;O. Elbrønd;H. Søgaard
鼻施耐德乳头状瘤是一种独特的病变，涉及鼻腔和鼻窦粘膜。组织学上最常呈表皮样，多发于鼻中隔和鼻腔外侧壁两个部位。关于这些肿瘤的医学文献包含了大量关于命名的矛盾，并且使用了不少于54个单独的名称。讨论了同义词，并提出了施耐德乳头状瘤这一术语作为最合适的替代。本研究包括83例施耐德乳头状瘤患者，分析其病史、临床和放射学表现、治疗方法、病理切片、复发和相关恶性肿瘤。组织学和临床特征对预测复发无帮助，但复发率与治疗方式有关；17%的复发率采用鼻外入路（侧鼻切开术），59%的复发率采用鼻内入路并有限切除。施耐德乳头状瘤合并鳞状细胞癌7例。4例（5%）患者在首发时同时表现为乳头状瘤和癌，3例（4%）患者随后发展为癌。由于不充分切除后经常复发，并且室间隔和侧壁乳头状瘤都可能伴有恶性肿瘤，因此提倡激进的手术，对整个标本进行彻底的组织学检查，并进行仔细的随访。
Nasal Schneiderian papillomas are unique lesions involving the mucosa of the nasal cavity and paranasal sinuses. Most often epidermoid in histological appearance, they favour 2 sites: the septum and the lateral wall of the nasal cavity. The medical literature on these tumours contains a plethora of contradictions concerning the nomenclature and no less than 54 separate designations are used. The synonyms are discussed and the term Schneiderian papilloma is proposed as the most suitable alternative. This study includes 83 patients with Schneiderian papillomas in whom the history, clinical and radiological findings, treatment procedures, pathological sections, recurrences, and associated malignancies were analyzed. Histological and clinical features were not helpful in predicting recurrence, but the recurrence rate was related to the treatment modalities; with 17% recurrences using an extranasal approach (lateral rhinotomy) and 59% using intranasal approach with limited excision. Schneiderian papillomas were associated with squamous cell carcinoma in 7 patients. Simultaneous papilloma and carcinoma were demonstrated in 4 patients at presentation (5%) and subsequently developing carcinoma in 3 patients (4%). As recurrences are frequent after inadequate removal and as association with maligancies may occur in both septal and lateral wall papillomas, radical aggressive surgery, thorough histological examination of the entire specimen, and careful follow-up are advocated.