Using adaptive magnetic resonance image-guided radiation therapy for treatment of inoperable pancreatic cancer
Using adaptive magnetic resonance image-guided radiation therapy for treatment of inoperable pancreatic cancer
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DOI：
10.1002/cam4.2100
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发表时间：
2019-05-01
期刊：
影响因子：
4
通讯作者：
Lee, Percy P.
中科院分区：
文献类型：
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作者：
Rudra, Soumon;Jiang, Naomi;Lee, Percy P.
背景自适应磁共振成像引导放射治疗（MRgRT）可以增加肿瘤剂量，同时最大限度地减少正常组织剂量。我们评估了无法手术的胰腺癌患者使用MRgRT（有或无剂量递增）治疗的结局。方法回顾性分析44例不能手术的胰腺癌患者行MRgRT治疗的临床资料。治疗包括常规分割、低分割和立体定向体部放射治疗。患者分为高剂量组（生物有效剂量[BED10] >70）和标准剂量组（BED10
Background Adaptive magnetic resonance imaging-guided radiation therapy (MRgRT) can escalate dose to tumors while minimizing dose to normal tissue. We evaluated outcomes of inoperable pancreatic cancer patients treated using MRgRT with and without dose escalation. Methods We reviewed 44 patients with inoperable pancreatic cancer treated with MRgRT. Treatments included conventional fractionation, hypofractionation, and stereotactic body radiation therapy. Patients were stratified into high-dose (biologically effective dose [BED10] >70) and standard-dose groups (BED10