HLA-A locus mismatches and development of antibodies to HLA after lung transplantation correlate with the development of bronchiolitis obliterans syndrome
HLA-A locus mismatches and development of antibodies to HLA after lung transplantation correlate with the development of bronchiolitis obliterans syndrome
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DOI：
10.1097/00007890-199803150-00008
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发表时间：
1998-03-15
期刊：
影响因子：
6.2
通讯作者：
Patterson, GA
中科院分区：
文献类型：
--
作者：
Sundaresan, S;Mohanakumar, T;Patterson, GA
背景闭塞性细支气管炎综合征（BOS）是肺移植（LT）后发病和死亡的最常见原因。方法：回顾性分析112例肝移植患者的临床和免疫学指标，其中94例存活3个月以上，随访至少21个月，以肺功能下降（FEV1）为标准确定BOS
Background. Bronchiolitis obliterans syndrome (BOS) is the most common cause of morbidity and mortality after lung transplantation (LT). A retrospective analysis of clinical and immunologic variables were done to identify those that might predict the development of BOS,Methods, Of 112 LT performed over a 42-month interval, 94 survived at least 3 months and form the basis of this analysis, There was a minimum of 21 months follow-up, BOS was defined on the basis of declining spirometry (FEV1