Technique for enhanced accuracy and reliability in non-human primate stereotaxy
Technique for enhanced accuracy and reliability in non-human primate stereotaxy
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DOI：
10.1016/j.jneumeth.2006.01.025
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发表时间：
2006-09-30
影响因子：
3
通讯作者：
Lonser, Russell R.
中科院分区：
文献类型：
--
作者：
Walbridge, Stuart;Murad, Gregory J. A.;Lonser, Russell R.
尽管提高非人类灵长类动物立体定位的准确性和可靠性很重要，但使用目前描述的技术仍存在一些局限性。为了克服这些问题，我们提出了一种简单的普遍可用的方法，将术前磁共振成像和非手术创建参考点(牙齿标记)相结合。我们发现，这种方法提高了立体定向的可靠性，并允许在远离术前成像的时间点进行准确的、可重复性的立体定位。爱思唯尔出版公司(Elsevier B.V.)
Despite the importance of enhancing the accuracy and reliability of non-human primate stereotaxy, a number of limitations exist using currently described techniques. To overcome these problems, we present a simple universally available approach that combines pre-operative magnetic resonance imaging and the non-surgical creation of reference points (teeth marking). We have found that this approach improves stereotaxic targeting reliability and permits accurate reproducible stereotaxic localization at time points distant from the pre-operative imaging. Published by Elsevier B.V.