Foetal antigens cross-reactive with tumour-specific transplantation antigens.
Foetal antigens cross-reactive with tumour-specific transplantation antigens.
复制标题
胎儿抗原与肿瘤特异性移植抗原发生交叉反应。
DOI：
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发表时间：
1973
期刊：
影响因子：
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通讯作者：
SAMUEL A. WELLS JUN.
中科院分区：
文献类型：
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作者：
BERNARD P. Lemevel;SAMUEL A. WELLS JUN.
大多数探索“胎儿抗原”和实验性肿瘤细胞抗原之间关系的研究人员都使用了由致瘤病毒诱导的啮齿动物肿瘤。他们通常发现，如果成年动物以适当的方式暴露在一定年龄的胎儿组织中，就会产生一种免疫力，这种免疫力似乎与肿瘤细胞抗原发生交叉反应，各种体内和体外技术都证明了这一点1 - 4。
MOST investigators exploring the relationship between “foetal antigens” and the antigens of experimental tumour cells have used rodent neoplasms induced by oncogenic viruses. They usually found that if the adult animal is exposed to foetal tissue of a certain age and in an appropriate fashion, an immunity develops which seems to be cross-reactive with tumour cell antigens demonstrable by various in vivo and in vitro techniques1–4.