Improving the detection limit of anion-selective electrodes: an iodide-selective membrane with a nanomolar detection limit.
Improving the detection limit of anion-selective electrodes: an iodide-selective membrane with a nanomolar detection limit.
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DOI：
10.1021/ac026454r
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发表时间：
2003-06
影响因子：
7.4
通讯作者：
Adam Malon;A. Radu;W. Qin;Yu Qin;A. Ceresa;M. Maj-Zurawska;E. Bakker;E. Pretsch
中科院分区：
文献类型：
--
作者：
Adam Malon;A. Radu;W. Qin;Yu Qin;A. Ceresa;M. Maj-Zurawska;E. Bakker;E. Pretsch
通过优化内溶液和膜组成，提高了阴离子选择电极（ISE）的检测下限和选择性。使用基于最近描述的离子载体[9]汞碳硼烷-3的膜，碘化物的检测限达到2 × 10（-9）M。尽管如此，改进不如阳离子交换元件的情况明显。这主要是因为迄今为止还没有已知的阴离子伊势具有极高的阳离子ISE选择性。如果膜不包含离子载体，则离子交换剂从膜浸出到样品中也是相关的限制因素，除了非常高亲脂性的离子交换剂。
The lower detection limit and the selectivity behavior of anion-selective electrodes (ISEs) are improved by using optimized inner solutions and membrane compositions. With a membrane based on the recently described ionophore [9]mercuracarborand-3, a detection limit of 2 x 10(-9) M has been achieved for iodide. Nevertheless, the improvements are less pronounced than in the case of cation ISEs. This is mainly due to the fact that so far no anion ISE is known with the extremely high selectivities of cation ISEs. If the membrane does not contain an ionophore, leaching of the ion exchanger from the membrane into the sample is also a relevant limiting factor except for ion exchangers of very high lipophilicity.