Dosimetric evaluation of Acuros XB Advanced Dose Calculation algorithm in heterogeneous media.
Dosimetric evaluation of Acuros XB Advanced Dose Calculation algorithm in heterogeneous media.
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DOI：
10.1186/1748-717x-6-82
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发表时间：
2011-07-19
期刊：
影响因子：
--
通讯作者：
Cozzi L
中科院分区：
文献类型：
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作者：
Fogliata A;Nicolini G;Clivio A;Vanetti E;Cozzi L
实现了一项研究，以评估和确定一个新的算法的光子剂量计算时，适用于非均匀介质的相对品质因数。将Varian Eclipse治疗计划系统中实施的新Acuros XB算法与Monte Carlo方法（VMC++）和分析各向异性算法（AAA）进行了比较。该研究是在具有简单几何结构的虚拟幻影中进行的。不同材料和密度的插入物被包括在由肌肉和HU = 0构建的体模中（设置“A”）：正常肺（肺，0.198 g/cm 3）;轻度肺（肺，0.035 g/cm 3）;骨（骨，1.798 g/cm 3）;另一个幻影（设置“B”）由脂肪材料构建，包括薄层骨（1.85 g/cm 3）、脂肪（0.92 g/cm 3）、软骨（1.4745 g/cm 3）、空气（0.0012 g/cm 3）。对6和15 MV光子束以及大（13 × 13 cm 2）和小（2.8 × 13 cm 2）场进行了研究。在平行于射束中心轴的平面中，提供了深度剂量曲线、横向剖面和伽马分析（3 mm/3%和2 mm/2%距离一致性/剂量差异标准）的结果;假定Monte Carlo模拟作为参考。Acuros XB给出的平均伽马一致性（3 mm/3%标准）分别为100%、86%和100%（正常肺、轻度肺和骨设置），以及剂量至中等计算。对于AAA，相同的数字分别为86%、11%和100%，其中仅可能将剂量重新调整为水计算。总之，Acuros XB算法为异质性管理提供了一种有效且准确的蒙特卡罗计算替代方案。
A study was realised to evaluate and determine relative figures of merit of a new algorithm for photon dose calculation when applied to inhomogeneous media. The new Acuros XB algorithm implemented in the Varian Eclipse treatment planning system was compared against a Monte Carlo method (VMC++), and the Analytical Anisotropic Algorithm (AAA). The study was carried out in virtual phantoms characterized by simple geometrical structures. An insert of different material and density was included in a phantom built of skeletal-muscle and HU = 0 (setting "A"): Normal Lung (lung, 0.198 g/cm3); Light Lung (lung, 0.035 g/cm3); Bone (bone, 1.798 g/cm3); another phantom (setting "B") was built of adipose material and including thin layers of bone (1.85 g/cm3), adipose (0.92 g/cm3), cartilage (1.4745 g/cm3), air (0.0012 g/cm3). Investigations were performed for 6 and 15 MV photon beams, and for a large (13 × 13 cm2) and a small (2.8 × 13 cm2) field. Results are provided in terms of depth dose curves, transverse profiles and Gamma analysis (3 mm/3% and 2 mm/2% distance to agreement/dose difference criteria) in planes parallel to the beam central axis; Monte Carlo simulations were assumed as reference. Acuros XB gave an average gamma agreement, with a 3 mm/3% criteria, of 100%, 86% and 100% for Normal Lung, Light Lung and Bone settings, respectively, and dose to medium calculations. The same figures were 86%, 11% and 100% for AAA, where only dose rescaled to water calculations are possible. In conclusion, Acuros XB algorithm provides a valid and accurate alternative to Monte Carlo calculations for heterogeneity management.