Phylogenetic analysis of the plant-specific Zinc Finger-Homeobox and Mini Zinc Finger gene families
Phylogenetic analysis of the plant-specific Zinc Finger-Homeobox and Mini Zinc Finger gene families
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DOI：
10.1111/j.1744-7909.2008.00681.x
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发表时间：
2008-08-01
影响因子：
11.4
通讯作者：
Ma, Hong
中科院分区：
文献类型：
--
作者：
Hu, Wei;dePamphilis, Claude W.;Ma, Hong
锌指同源结构域蛋白(ZHD)存在于许多植物中，然而，ZHD基因家族的进化历史在很大程度上仍不清楚。我们在这里表明，ZHD基因是植物特有的，几乎所有的内含子都没有，并且与只拥有锌指的迷你锌指(MIF)基因有关。对典型陆地植物ZHD基因的系统发育分析表明，非种子植物的ZHD基因占据了基本位置，被子植物的同源基因形成了7个不同的分支。几个分支包含两个或两个以上主要被子植物类群的基因，包括真子叶、单子叶、木兰科和其他基生被子植物，这表明在开花植物多样化之前发生了几次重复。此外，特定的血统经历了更新的复制。与ZHD基因不同，MIF仅在种子植物中发现，可能是在种子植物分化之前由于ZHD同源结构域的丢失而产生的。此外，MIF基因也经历了相对较新的基因复制。最后，基因组复制可能在很大程度上促进了被子植物家族规模的扩大，并导致了这些基因高度的功能冗余/重叠。
Zinc finger-homeodomain proteins (ZHD) are present in many plants; however, the evolutionary history of the ZHD gene family remains largely unknown. We show here that ZHD genes are plant-specific, nearly all intronless, and related to MINI ZINC FINGER (MIF) genes that possess only the zinc finger. Phylogenetic analyses of ZHD genes from representative land plants suggest that non-seed plant ZHD genes occupy basal positions and angiosperm homologs form seven distinct clades. Several clades contain genes from two or more major angiosperm groups, including eudicots, monocots, magnoliids, and other basal angiosperms, indicating that several duplications occurred before the diversification of flowering plants. In addition, specific lineages have experienced more recent duplications. Unlike the ZHD genes, MIFs are found only from seed plants, possibly derived from ZHDs by loss of the homeodomain before the divergence of seed plants. Moreover, the MIF genes have also undergone relatively recent gene duplications. Finally, genome duplication might have contributed substantially to the expansion of family size in angiosperms and caused a high level of functional redundancy/overlap in these genes.